Diet-modified sex hormone metabolism : is this the way forward in recurrent respiratory papillomatosis and squamous carcinoma prophylaxis ?

We report two cases of recurrent laryngeal papillomatosis in women who subsequently developed squamous cell carcinoma as they approached the climacteric. The role of human papilloma virus (HPV) and oestrogen metabolism is outlined. The use of indoles from cruciferous vegetables is also discussed.

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Bibliographic Details
Published in:Journal of laryngology and otology 1995-09, Vol.109 (9), p.873-875
Main Authors: COLQUHOUN-FLANNERY, W, CARRUTH, J. A. S
Format: Article
Language:English
Subjects:
Adult
Animals
Biological and medical sciences
Bronchial Neoplasms - metabolism
Carcinoma, Squamous Cell - metabolism
Carcinoma, Squamous Cell - surgery
Carcinoma, Squamous Cell - virology
Cell Transformation, Neoplastic - drug effects
Estrogens - metabolism
Female
Humans
Laryngeal Neoplasms - metabolism
Laryngeal Neoplasms - surgery
Laryngeal Neoplasms - virology
Laser Therapy
Lung Neoplasms - metabolism
Medical sciences
Mice
Neoplasm Recurrence, Local
Neoplasms, Second Primary
Otorhinolaryngology. Stomatology
Papilloma - metabolism
Papilloma - surgery
Papilloma - virology
Tumors
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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Description
Summary:We report two cases of recurrent laryngeal papillomatosis in women who subsequently developed squamous cell carcinoma as they approached the climacteric. The role of human papilloma virus (HPV) and oestrogen metabolism is outlined. The use of indoles from cruciferous vegetables is also discussed.
ISSN:0022-2151
1748-5460
DOI:10.1017/S002221510013155X