Anti-Jo-1 Syndrome presenting as cryptogenic organizing pneumonia

A 50-year-old Chinese lady presented with subacute onset of dyspnoea, bilateral infiltrates on chest X-ray and type I respiratory failure. There were minor symptoms of arthralgia and myalgia. Subsequent investigations confirmed that she had organizing pneumonia, polymyositis and serum anti-Jo-1 anti...

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Bibliographic Details
Published in:Respiratory medicine 1995-10, Vol.89 (9), p.639-641
Main Authors: Chan, W.M., Ip, M., Lau, C.S., Wang, E., Peh, W.C.G.
Format: Article
Language:English
Subjects:
Autoantibodies - analysis
Biological and medical sciences
Female
Humans
Medical sciences
Middle Aged
Pneumonia - etiology
Polymyositis - complications
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Syndrome
Threonine-tRNA Ligase - immunology
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Summary:A 50-year-old Chinese lady presented with subacute onset of dyspnoea, bilateral infiltrates on chest X-ray and type I respiratory failure. There were minor symptoms of arthralgia and myalgia. Subsequent investigations confirmed that she had organizing pneumonia, polymyositis and serum anti-Jo-1 antibody. Treatment with corticosteroids resulted in prompt improvement of the respiratory condition and myositis.
ISSN:0954-6111
1532-3064
DOI:10.1016/0954-6111(95)90237-6