Risk Factors and Atherosclerosis in Youth Autopsy Findings of the Bogalusa Heart Study

The Collaborative Pathology Study is one of the most impressive programs of the Bogalusa Heart Study. Attempts are made to obtain complete and uniform necropsy coverage of all deceased young people who may have been examined in the Bogalusa Heart Study. Since 1978, autopsy specimens have been collec...

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Bibliographic Details
Published in:The American journal of the medical sciences 1995-12, Vol.310, p.S37-S41
Main Authors: Tracy, Richard E., Newman, William P., Wattigney, Wendy A., Berenson, Gerald S.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Arteriosclerosis - etiology
Arteriosclerosis - pathology
Atherosclerosis
Autopsy
Child
Child, Preschool
Cholesterol, LDL - analysis
Cholesterol, VLDL - analysis
Coronary artery disease
Coronary Vessels - pathology
Fatty streaks
Fibrous plaques
Humans
Hypertension
Infant
Infant, Newborn
Kidney - pathology
Risk Factors
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Summary:The Collaborative Pathology Study is one of the most impressive programs of the Bogalusa Heart Study. Attempts are made to obtain complete and uniform necropsy coverage of all deceased young people who may have been examined in the Bogalusa Heart Study. Since 1978, autopsy specimens have been collected from 190 deaths, representing 65% of all known deaths in the study age category. The relation of antemortem risk factors for cardiovascular disease to early atherosclerotic lesions in the aorta and coronary arteries was assessed in those individuals previously examined in the Bogalusa Heart Study (N=59). Aortic fatty streaks were strongly related to both total and low-density lipoprotein (LDL) cholesterol (r=0.62 P
ISSN:0002-9629
1538-2990
DOI:10.1097/00000441-199512000-00007