Alpha-fetoprotein-producing adenocarcinoma of the sigmoid colon with possible hepatoid differentiation

A patient with adenocarcinoma of the sigmoid colon producing alpha-fetoprotein (AFP) is described. Hepatoid differentiation is suggested by the morphological appearance and production of hepatic-type AFP. The possible histogenesis of such a tumor is discussed.

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Bibliographic Details
Published in:Pathology 1995-07, Vol.27 (3), p.277-279
Main Authors: Hocking, Glenn R., Shembrey, Michael, Hay, David, Östör, Andrew G.
Format: Article
Language:English
Subjects:
Adenocarcinoma
Adenocarcinoma - metabolism
Adenocarcinoma - pathology
Adult
alpha-fetoprotein
alpha-Fetoproteins - biosynthesis
Biological and medical sciences
Carcinoma, Hepatocellular - pathology
colon
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Medical sciences
Sigmoid Neoplasms - metabolism
Sigmoid Neoplasms - pathology
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tumors
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Description
Summary:A patient with adenocarcinoma of the sigmoid colon producing alpha-fetoprotein (AFP) is described. Hepatoid differentiation is suggested by the morphological appearance and production of hepatic-type AFP. The possible histogenesis of such a tumor is discussed.
ISSN:0031-3025
1465-3931
DOI:10.1080/00313029500169113