Characterization of Streptococcus sanguis Isolated from Patients with Behçet's Disease

• Published in: MICROBIOLOGY and IMMUNOLOGY 1995, Vol.39(9), pp.729-732
• Main Authors: Yokota, Kenji, Hayashi, Shynji, Araki, Yoshio, Isogai, Emiko, Kotake, Satoshi, Yoshikawa, Kouji, Fujii, Nobuhiro, Hirai, Yoshikazu, Oguma, Keiji
• Format: Article
• Language: English
• Subjects: Behcet Syndrome - microbiology; Biological and medical sciences; Cell Wall - chemistry; Cell wall constituents; DNA, Bacterial - analysis; DNA-DNA hybridization; Humans; Medical sciences; Mucocutaneous Lymph Node Syndrome - microbiology; Polysaccharides, Bacterial - analysis; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Streptococcus; Streptococcus - chemistry; Streptococcus sanguinis; Streptococcus sanguis; Streptococcus sanguis - chemistry; Streptococcus sanguis - isolation & purification; Streptococcus sanguis - ultrastructure
• ISSN: 0385-5600; 1348-0421
• DOI: 10.1111/j.1348-0421.1995.tb03249.x

The DNA homology and cell wall sugar constituents of eight Streptococcus sanguis(-like) strains, three isolated from the patients with Behçet's disease (BD114-23, BD113-20, BD118-1), two from patients with Kawasaki disease (MCLS-1, MCLS-2), and three type and reference strains of ATCC (ATCC10556T: S. sanguis, ATCC10557: S. oralis, and ATCC10558T: S. gordonii) were analyzed. Strains BD114-23 and BD118-1 showed high DNA homology to ATCC10556T, and their cell wall constituents were identical. Conversely, BD113-20, MCLS-1, MCLS-2, and ATCC10557 showed little DNA homology to ATCC10556T and ATCC10558T, but showed approximately 50 to 60% homology to each other. The cell wall constituents of BD113-20, MCLS-1, MCLS-2, and ATCC10557, however, were somewhat different, indicating that some of the clinical isolates have different characters from those of the three ATCC strains.