BCG vaccination against tuberculosis: past disappointments and future hopes

Three billion doses of the bacille Calmette-Guérin (BCG) vaccine have been given over the past 60 years. BCG has a widely variable ability to protect humans against tuberculosis. This article examines some of the reasons for this variability, and discusses ways in which BCG vaccination might be impr...

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Bibliographic Details
Published in:Trends in microbiology (Regular ed.) 1995-10, Vol.3 (10), p.397-401
Main Authors: Roche, Paul W, Triccas, James A, Winter, Nathalie
Format: Article
Language:English
Subjects:
Animals
BCG Vaccine - administration & dosage
Forecasting
Humans
Tuberculosis - prevention & control
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Summary:Three billion doses of the bacille Calmette-Guérin (BCG) vaccine have been given over the past 60 years. BCG has a widely variable ability to protect humans against tuberculosis. This article examines some of the reasons for this variability, and discusses ways in which BCG vaccination might be improved.
ISSN:0966-842X
1878-4380
DOI:10.1016/S0966-842X(00)88986-6