Investigation of applicability of alanine and radiochromic detectors to dosimetry of proton clinical beams

Cancer therapy studies using proton accelarators are underway in several major medical centers in the U.S., Russia, Japan and elsewhere. To facilitate dosimetry intercomparisons between these laboratories, alanine-based detectors produced at the National Institute of Standards and Technology and Com...

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Bibliographic Details
Published in:Applied radiation and isotopes 1995-12, Vol.46 (12), p.1355-1362
Main Authors: Nichiporov, D., Kostjuchenko, V., Puhl, J.M., Bensen, D.L., Desrosiers, M.F., Dick, C.E., Mclaughlin, W.L., Kojima, T., Coursey, B.M., Zink, S.
Format: Article
Language:English
Subjects:
Alanine
Chromium Radioisotopes
Electron Spin Resonance Spectroscopy
Humans
Japan
Neoplasms - radiotherapy
Particle Accelerators
Phantoms, Imaging
Protons
Radiotherapy Dosage
Russia
United States
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Summary:Cancer therapy studies using proton accelarators are underway in several major medical centers in the U.S., Russia, Japan and elsewhere. To facilitate dosimetry intercomparisons between these laboratories, alanine-based detectors produced at the National Institute of Standards and Technology and Commercially available radiochromic films were studied for their possible use as passive transfer dosimeters for clinical proton beams. Evaluation of characteristics of these instruments, including the LET dependence of their response of proton energy, was carried out at the Institute of Theoretical and Experimental Physics. Results of absolute dose measurements were regarded as a preliminary step of dose intercomparison between ITEP and NIST. Measurements made in a number of experiments showed average agreement between the ITEP and NIST dosimetry standards to 2.5%.
ISSN:0969-8043
1872-9800
DOI:10.1016/0969-8043(95)00213-W