Effect of Angiotensin Converting Enzyme Inhibition on Airway Conductance during Hypocapnic Hyperventilation in Normal Subjects

In nine normal subjects, specific airway conductance was measured by whole body plethysmography before and immediately after hypocapnic hyperventilation. This procedure, forced expiratory manoeuvres and arterial blood pressure measurements were carried out before and 4 h after placebo and the angiot...

Full description

Saved in:
Bibliographic Details
Published in:Pulmonary pharmacology (Edinburgh) 1995-02, Vol.8 (1), p.49-51
Main Authors: Jamison, J.P., Glover, P.J.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Angiotensin converting enzyme inhibitor, Airways, Airway conductance, Hyperventilation, Hypocapnia
Angiotensin-Converting Enzyme Inhibitors - pharmacology
Bronchoconstriction - drug effects
Double-Blind Method
Enalapril - pharmacology
Humans
Hydrogen-Ion Concentration
Hyperventilation - physiopathology
Hypocapnia - physiopathology
Male
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In nine normal subjects, specific airway conductance was measured by whole body plethysmography before and immediately after hypocapnic hyperventilation. This procedure, forced expiratory manoeuvres and arterial blood pressure measurements were carried out before and 4 h after placebo and the angiotensin converting enzyme inhibitor, enalapril, in a double-blind, randomized study design. Bronchoconstriction to hypocapnic hyperventilation was shown by a reduction in specific airway conductance on all occasions ( P
ISSN:0952-0600
1522-9637
DOI:10.1006/pulp.1995.1007