Uterine carcinomas in mother cats after intrafetal inoculation of allogeneic tumor cells (K248 C and P)

Three out of 13 queens that had undergone injection of tumor cells from an allogeneic feline mammary carcinoma cell line through the wall of the pregnant uterus developed a carcinoma of the uterus. The possible role of immune tolerance associated with pregnancy and/or major histocompatibility comple...

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Bibliographic Details
Published in:Veterinary immunology and immunopathology 1995-06, Vol.46 (3), p.361-366
Main Authors: Minke, J.M.H.M., Hensen, E.J., Misdorp, W.
Format: Article
Language:English
Subjects:
Animals
Carcinoma - immunology
Carcinoma - pathology
Carcinoma - veterinary
CARCINOMAS
CARCINOME
Cat Diseases - immunology
Cat Diseases - pathology
CATS
CHAT
Female
Fetus
Follow-Up Studies
GATO
Immune Tolerance
Injections - veterinary
MAJOR HISTOCOMPATIBILITY COMPLEX
Major Histocompatibility Complex - immunology
Mammary Neoplasms, Experimental - immunology
Mammary Neoplasms, Experimental - pathology
Neoplasm Metastasis
Neoplasm Transplantation - veterinary
Pregnancy
Pregnancy Complications, Neoplastic - immunology
Pregnancy Complications, Neoplastic - pathology
Pregnancy Complications, Neoplastic - veterinary
SISTEMA MHC
SYSTEME MHC
Transplantation, Homologous - veterinary
Tumor Cells, Cultured
Uterine Neoplasms - immunology
Uterine Neoplasms - pathology
Uterine Neoplasms - veterinary
UTERO
UTERUS
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Summary:Three out of 13 queens that had undergone injection of tumor cells from an allogeneic feline mammary carcinoma cell line through the wall of the pregnant uterus developed a carcinoma of the uterus. The possible role of immune tolerance associated with pregnancy and/or major histocompatibility complex (MHC) compatibility is discussed.
ISSN:0165-2427
1873-2534
DOI:10.1016/0165-2427(94)05368-3