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DNA marker-assisted selection of the polled condition in Charolais cattle

Five Charolais families known to segregate for both horned and polled were selected and tested for linkage analysis by use of microsatellites and karyotyping for Robertsonian translocation 1;29. No recombinants were found between any of these markers and the polled phenotype or each other. When stat...

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Published in:	Mammalian genome 1995-10, Vol.6 (10), p.710-713
Main Authors:	Schmutz, S M, Marquess, F L, Berryere, T G, Moker, J S
Format:	Article
Language:	English
Subjects:	Animals Cattle - genetics Chromosome Mapping Female Horns Karyotyping Male Mammalia Microsatellite Repeats - genetics Pedigree Phenotype Translocation, Genetic
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creator	Schmutz, S M Marquess, F L Berryere, T G Moker, J S
description	Five Charolais families known to segregate for both horned and polled were selected and tested for linkage analysis by use of microsatellites and karyotyping for Robertsonian translocation 1;29. No recombinants were found between any of these markers and the polled phenotype or each other. When statistical analysis was performed, the logarithm of the odds (LOD) indicated that there was 100% linkage occurring between the markers and the phenotype (p < 0.001). These microsatellite markers, TGLA49 and BM6438, can be assumed to be very close to the actual gene that determines the polled phenotype. Another linked marker, SOD1, was physically mapped, which places all of these markers within 1q12-14, very near the centromere of Chromosome (Chr) 1. A homozygous polled cow was identified in this study by following the alleles at both markers and the phenotypes in her family.
doi_str_mv	10.1007/BF00354293
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subjects	Animals Cattle - genetics Chromosome Mapping Female Horns Karyotyping Male Mammalia Microsatellite Repeats - genetics Pedigree Phenotype Translocation, Genetic
title	DNA marker-assisted selection of the polled condition in Charolais cattle
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