A case report suggesting a common pathogenesis for IgA nephropathy and Henoch-Schönlein purpura

A 7-year-old boy who had been followed for asymptomatic haematuria and elevated serum IgA levels developed Henoch-Schönlein purpura (HSP) after a streptococcal infection of the tonsils. Findings on renal biopsy were compatible with mild IgA nephropathy (IgAN); tonsillectomy was also performed as he...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 1994-12, Vol.8 (6), p.750-751
Main Authors: KANEKO, K, SUZUKI, Y, KIYA, K, FUKUDA, Y, YABUTA, K
Format: Article
Language:English
Subjects:
Biological and medical sciences
Child
Glomerulonephritis
Glomerulonephritis, IGA - etiology
Glomerulonephritis, IGA - pathology
Hematuria - complications
Humans
Immunoglobulin A - blood
Male
Medical sciences
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Purpura, Schoenlein-Henoch - etiology
Streptococcal Infections - complications
Streptococcal Infections - immunology
Tonsillitis - complications
Tonsillitis - immunology
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Summary:A 7-year-old boy who had been followed for asymptomatic haematuria and elevated serum IgA levels developed Henoch-Schönlein purpura (HSP) after a streptococcal infection of the tonsils. Findings on renal biopsy were compatible with mild IgA nephropathy (IgAN); tonsillectomy was also performed as he had chronic tonsillitis. This case suggests that there is a common pathogenesis for IgAN and HSP, at least in some patients.
ISSN:0931-041X
1432-198X
DOI:10.1007/BF00869110