Oral ciprofloxacin as prophylaxis in gastroduodenal surgery

One hundred and fifty patients undergoing gastroduodenal surgery were randomly allocated to receive intravenous (iv) cefuroxime, iv ciprofloxacin or oral ciprofloxacin as prophylaxis. There were no differences in the incidence of postoperative infection complications or duration of stay among the th...

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Bibliographic Details
Published in:The Journal of hospital infection 1995-07, Vol.30 (3), p.211-216
Main Authors: McArdle, C.S., Morran, C.G., Anderson, J.R., Pettit, L., Gemmell, C.G., Sleigh, J.D., Tillotson, G.S.
Format: Article
Language:English
Subjects:
Administration, Oral
Anti-Infective Agents - administration & dosage
Anti-Infective Agents - therapeutic use
Antibacterial agents
Antibiotic Prophylaxis
Antibiotics. Antiinfectious agents. Antiparasitic agents
Bacterial Infections - prevention & control
Biological and medical sciences
Cefuroxime - administration & dosage
Cefuroxime - therapeutic use
Ciprofloxacin
Ciprofloxacin - administration & dosage
Ciprofloxacin - therapeutic use
Duodenum - surgery
Female
Humans
Injections, Intravenous
Length of Stay - statistics & numerical data
Male
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Scotland
Stomach - surgery
Surgical Wound Infection - prevention & control
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Description
Summary:One hundred and fifty patients undergoing gastroduodenal surgery were randomly allocated to receive intravenous (iv) cefuroxime, iv ciprofloxacin or oral ciprofloxacin as prophylaxis. There were no differences in the incidence of postoperative infection complications or duration of stay among the three groups. Oral ciprofloxacin offers obvious advantages in terms of ease of administration and cost.
ISSN:0195-6701
1532-2939
DOI:10.1016/S0195-6701(95)90316-X