Vitamin E in intestinal fat malabsorption

This study was done on 5 patients suffering from tropical sprue (8-10 years' duration). Serum vitamin E level was significantly low in these patients. Cell-mediated immune mechanism assessed by using 2,4-dinitrochlorobenzene, a skin-sensitizing hapten, was also depressed. Polyneuropathy was als...

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Bibliographic Details
Published in:Annals of nutrition and metabolism 1995, Vol.39 (5), p.296-301
Main Authors: Ghalaut, Veena Singh, Ghalaut, Partap Singh, Kharb, Simmi, Singh, Ganesh Prasad
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
blood serum
cell-mediated immunity
delayed hypersensitivity
dietary fat
Digestive system
Dinitrochlorobenzene
Humans
Immunity, Cellular
intestinal absorption
Investigative techniques, diagnostic techniques (general aspects)
malabsorption
Medical sciences
Middle Aged
Nervous System Diseases - drug therapy
Original Paper
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
patients
polyneuropathy
replacement
Skin Tests
Sprue, Tropical - complications
Sprue, Tropical - drug therapy
Sprue, Tropical - immunology
symptoms
tropical sprue
vitamin deficiencies
vitamin E
Vitamin E - administration & dosage
Vitamin E - therapeutic use
Vitamin E Deficiency - complications
Vitamin E Deficiency - immunology
vitamin supplements
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Description
Summary:This study was done on 5 patients suffering from tropical sprue (8-10 years' duration). Serum vitamin E level was significantly low in these patients. Cell-mediated immune mechanism assessed by using 2,4-dinitrochlorobenzene, a skin-sensitizing hapten, was also depressed. Polyneuropathy was also observed. Repletion of vitamin deficiency was associated with marked improvement in T-cell functions and neuropathy.
ISSN:0250-6807
1421-9697
DOI:10.1159/000177876