The immunorejection of neoplasia in a theoretical model

A theoretical model is presented based on the idea that the immune system of a patient with a tumour can cross-react against transplanted normal foreign cells as well as against the patient's own neoplastic cells, thereby rejecting both. This hypothesis is shown in a diagram, the potential use...

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Bibliographic Details
Published in:Medical hypotheses 1995-09, Vol.45 (3), p.282-286
Main Author: Pellettieri, L.
Format: Article
Language:English
Subjects:
Antigens, Neoplasm - immunology
Antineoplastic agents
Biological and medical sciences
Cell Transplantation
Cross Reactions
Graft Rejection - immunology
Histocompatibility
HLA Antigens - immunology
Host vs Graft Reaction
Humans
Immunotherapy
Medical sciences
Models, Immunological
Neoplasms - immunology
Neoplasms - therapy
Pharmacology. Drug treatments
Transplantation Immunology
Transplantation, Homologous - immunology
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Description
Summary:A theoretical model is presented based on the idea that the immune system of a patient with a tumour can cross-react against transplanted normal foreign cells as well as against the patient's own neoplastic cells, thereby rejecting both. This hypothesis is shown in a diagram, the potential use of which is discussed.
ISSN:0306-9877
1532-2777
DOI:10.1016/0306-9877(95)90118-3