Proteinaceous lymphadenopathy in a patient with known rheumatoid arthritis : case report and review of literature

We describe a case of proteinaceous lymphadenopathy (also called lymph node hyalinosis) in a 30-yr-old woman with known rheumatoid arthritis (RA). Amyloidosis was excluded by negative staining with congo red viewed with and without polarized light. Proteinaceous lymphadenopathy should be included in...

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Bibliographic Details
Published in:British journal of rheumatology 1995-11, Vol.34 (11), p.1087-1089
Main Authors: AL RIKABI, A. C, NADDAF, H. O, AL BALLA, S. R, AL SOHAIBANI, M. O
Format: Article
Language:English
Subjects:
Adult
Amyloidosis - diagnosis
Amyloidosis - pathology
Arthritis, Rheumatoid - complications
Arthritis, Rheumatoid - diagnosis
Arthritis, Rheumatoid - pathology
Biological and medical sciences
Biopsy, Needle
Diagnosis, Differential
Diseases of the osteoarticular system
Female
Humans
Inflammatory joint diseases
Lymph Nodes - chemistry
Lymph Nodes - pathology
Lymphatic Diseases - complications
Lymphatic Diseases - diagnosis
Medical sciences
Proteins - analysis
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Summary:We describe a case of proteinaceous lymphadenopathy (also called lymph node hyalinosis) in a 30-yr-old woman with known rheumatoid arthritis (RA). Amyloidosis was excluded by negative staining with congo red viewed with and without polarized light. Proteinaceous lymphadenopathy should be included in the differential diagnosis of patients with lymphadenopathy and long-standing RA. The histopathologist should be familiar with the morphological appearances of this condition, which can be confused with amyloidosis. It appears that there is a good clinical response in RA-associated proteinaceous lymphadenopathy following successful treatment of arthritis.
ISSN:0263-7103
1460-2172