FENTANYL-DROPERIDOL SUPPLEMENTATION OF RAPID SEQUENCE INDUCTION IN THE PRESENCE OF SEVERE PREGNANCY-INDUCED AND PREGNANCY-AGGRAVATED HYPERTENSION

Twenty-six patients manifesting severe pregnancy-induced (PIH) or pregnancy-aggravated (PAH) hypertension who presented for emergency Caesarean section under general anaesthesia were studied. All patients came from a previously identified high risk group—namely > 25 yr, multiparous and with diast...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1987-11, Vol.59 (11), p.1381-1391
Main Authors: LAWES, E.G., DOWNING, J.W., DUNCAN, P.W., BLAND, B., LAVIES, N., GANE, G.A.C.
Format: Article
Language:English
Subjects:
Abdominal surgery. Urology. Gynecology. Obstetrics
Adjuvants, Anesthesia
Adult
Anesthesia
Anesthesia depending on type of surgery
Anesthesia, General
Anesthesia, Obstetrical
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Apgar Score
Biological and medical sciences
Blood Pressure - drug effects
Cesarean Section
Droperidol - pharmacology
Emergencies
Female
Fentanyl - pharmacology
Humans
Hypertension - physiopathology
Infant, Newborn
Medical sciences
Middle Aged
Pregnancy
Pregnancy Complications, Cardiovascular - physiopathology
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Summary:Twenty-six patients manifesting severe pregnancy-induced (PIH) or pregnancy-aggravated (PAH) hypertension who presented for emergency Caesarean section under general anaesthesia were studied. All patients came from a previously identified high risk group—namely > 25 yr, multiparous and with diastolic arterial pressures sustained at > 120 mm Hg. Our standard accelerated induction technique for the management of severely hypertensive mothers was modified to include the use of fentanyl and droperidol before induction. This modification of the induction sequence produced a clinically significant amelioration of the reflex sympathetic hypertensive response to laryngoscopy and intubation in most mothers receiving antihypertensive therapy, without apparent deleterious effect in the immediate postoperative period to those neonates unaffected by intrauterine asphyxia.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/59.11.1381