Congenital cytomegalovirus infection

Objective: Congenital cytomegalovirus is the most common viral infection affecting approximately 1% of newborns. The virus can be transmitted to the fetus during both primary and recurrent infection. Although most of the infants are asymptomatic at birth, up to 15% develop late complications. The an...

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Bibliographic Details
Published in:European Journal of Obstetrics and Gynecology 1995-11, Vol.63 (1), p.7-16
Main Authors: Daniel, Yair, Gull, Ilan, Peyser, M.Reuben, Lessing, Joseph B.
Format: Article
Language:English
Subjects:
Antenatal diagnosis
Biological and medical sciences
CMV
Cytomegalovirus Infections - complications
Cytomegalovirus Infections - congenital
Cytomegalovirus Infections - diagnosis
Cytomegalovirus Infections - drug therapy
Cytomegalovirus Infections - economics
Cytomegalovirus Infections - prevention & control
Female
Human viral diseases
Humans
Infant, Newborn
Infectious diseases
Medical sciences
Pregnancy
Prenatal Diagnosis
Prenatal screening
United States
Vaccine
Viral diseases
Viral diseases of the genital and urinary system
Viral Vaccines
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Summary:Objective: Congenital cytomegalovirus is the most common viral infection affecting approximately 1% of newborns. The virus can be transmitted to the fetus during both primary and recurrent infection. Although most of the infants are asymptomatic at birth, up to 15% develop late complications. The annual cost of treating cytomegalovirus infection complications in the USA is two billion US dollars. Many issues regarding cytomegalovirus infection such as routine screening, antenatal diagnosis and vaccination during pregnancy are unsettled and disputed. The aim of this article is to review the current literature on the subject and to draw some conclusions. Design: Review of the current literature. Conclusions: At present, it appears that there is no indication for routine prenatal screening, while other issues, such as the most accurate method for antenatal diagnosis and the indications for pregnancy termination are, as yet, unsettled.
ISSN:0301-2115
1872-7654
DOI:10.1016/0301-2115(95)02198-G