Continuous treatment modalities in acute renal failure

Continuous treatment modalities have become well established in the treatment of severely ill patients with acute renal failure since the introduction of continuous arteriovenous haemofiltration. However, this simple blood-pressure-driven treatment often fails to control azotaemia, especially in hae...

Full description

Saved in:
Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 1995-11, Vol.10 (11), p.2001-2008
Main Authors: KIEDORF, H, SIEBERTH, H. G
Format: Article
Language:English
Subjects:
Acute Kidney Injury - mortality
Acute Kidney Injury - therapy
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Emergency and intensive care: renal failure. Dialysis management
Hemofiltration - instrumentation
Hemofiltration - methods
Humans
Intensive care medicine
Medical sciences
Treatment Outcome
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Continuous treatment modalities have become well established in the treatment of severely ill patients with acute renal failure since the introduction of continuous arteriovenous haemofiltration. However, this simple blood-pressure-driven treatment often fails to control azotaemia, especially in haemodynamically unstable patients with hypercatabolism. The common feature of further developments in continuous treatment modalities, such as continuous arteriovenous haemodialysis, venovenous haemofiltration, or venovenous haemodialysis is their higher efficacy in controlling azotaemia. Venovenous forms of treatment involve considerably higher technical requirements. The main advantages of continuous forms of treatment as opposed to intermittent haemodialysis are greater haemodynamic stability and the possibility of adapting nutrition without restriction to the needs of the critically ill. The uninterrupted necessity for anticoagulants is the most important disadvantage. The question of whether patients may profit from the continuous elimination of mediators involved in acute renal or multiple organ failure is still open. In retrospective analysis continuous methods appear to reduce mortality in acute renal failure, but prospective randomized studies are necessary to clearly demonstrate a benefit of these methods as opposed to intermittent haemodialysis.
ISSN:0931-0509
1460-2385
1460-2385
DOI:10.1093/ndt/10.11.2001