Malignant lymphoma of mucosa associated lymphoid tissue: a new etiology of amyloidosis

Non Hodgkin Malignant lymphomas (NHML) o f mucosa associated lymphoid tissue (MALT) are known to have multiple involvement o f the digestive tract. We report one case, presenting with an in f iltrative process o f the jejuno-ileum, associating lym phoplasmacytoid proliferating cells and amyloidosis....

Full description

Saved in:
Bibliographic Details
Published in:Pathology, research and practice research and practice, 1995-12, Vol.191 (12), p.1203-1207
Main Authors: Caulet, S., Robert, I., Bardaxoglou, E., Noret, Ph, Tas, P., Le Prise, Y., Launois, B., Ramee, M.-P.
Format: Article
Language:English
Subjects:
Amyloid - analysis
Amyloidosis - etiology
Amyloidosis - pathology
Amyloidosis-immunoglobulinic amyloidosis
Female
Gastrointestinal tract
Humans
Immunocytic disorders
Immunohistochemistry
Intestinal Neoplasms - complications
Intestinal Neoplasms - pathology
Lympboma
Lymphoma, B-Cell, Marginal Zone - chemistry
Lymphoma, B-Cell, Marginal Zone - complications
Lymphoma, B-Cell, Marginal Zone - pathology
Middle Aged
Mucosa associated lymphoid tissue
Stomach Neoplasms - complications
Stomach Neoplasms - pathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Non Hodgkin Malignant lymphomas (NHML) o f mucosa associated lymphoid tissue (MALT) are known to have multiple involvement o f the digestive tract. We report one case, presenting with an in f iltrative process o f the jejuno-ileum, associating lym phoplasmacytoid proliferating cells and amyloidosis. The plasmacytoid cells expressed Alpha and scarce Mu heavy chains, and lambda light chain. Lympho-epithelial lesions were more obvious at the second site o f involvement, in the gastric mucosa. The amyloid substance was negative with the Amyloid A component antibody and gave a background noise with Alpha, Mu and lambda chains. No similar report o f amyloidosis associated with MALT NHML has been found in the literature.
ISSN:0344-0338
1618-0631
DOI:10.1016/S0344-0338(11)81127-1