Neonatal Malaria: a Clinical Study of Congenital and Transfusional Malaria

Thirty-one babies with neonatal malaria (congenital = 13, transfusional = 18) were treated over a period of 10 years at the Postgraduate Institute of Medical Education & Research, Chandigarh. Anaemia (100 per cent) pyrexia (90 per cent), splenomegaly (84 per cent), hepatomegaly (64 per cent), an...

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Bibliographic Details
Published in:Journal of tropical pediatrics (1980) 1987-10, Vol.33 (5), p.266-268
Main Authors: Thapa, B. R., Narang, A., Bhakoo, O. N.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Developing Countries
Female
Human protozoal diseases
Humans
India
Infant
Infant, Newborn
Infectious diseases
Malaria
Malaria - congenital
Malaria - transmission
Male
Medical sciences
Parasitic diseases
Plasmodium falciparum
Plasmodium vivax
Protozoal diseases
Transfusion Reaction
Tropical medicine
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Summary:Thirty-one babies with neonatal malaria (congenital = 13, transfusional = 18) were treated over a period of 10 years at the Postgraduate Institute of Medical Education & Research, Chandigarh. Anaemia (100 per cent) pyrexia (90 per cent), splenomegaly (84 per cent), hepatomegaly (64 per cent), and jaundice (22 per cent) were the presenting features. Three babies had cerebral malaria while one baby had intravascular haemolysis and acute renal failure. The mothers of 8 out of 13 babies with congenital malaria had malaria during the third trimester. Plasmodium vivax was found in 25 babies and Plasmodium falciparum in nine babies. Three babies had mixed infestations. Twenty-eight out of 30 babies responded to chloroquine therapy whereas two out of three babies with cerebral malaria had a fatal outcome.
ISSN:0142-6338
1465-3664
DOI:10.1093/tropej/33.5.266