Stage-specific gene expression in lymphatic filarial nematodes

Lymphatic filarial nematodes remain a significant cause of morbidity throughout much of the tropics. One approach to the development of rational control methods is an improved understanding of the basic biology of these organisms in relation to the mechanisms used to complete their life cycles. In t...

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Bibliographic Details
Published in:Parasitology Today 1996-11, Vol.12 (11), p.418-424
Main Authors: Devaney, E., Martin, S.A.M., Thompson, F.J.
Format: Article
Language:English
Subjects:
Biochemistry. Physiology. Immunology. Molecular biology
Biological and medical sciences
Brugia pahangi
Fundamental and applied biological sciences. Psychology
Invertebrates
Nemathelminthia. Plathelmintha
Physiology. Development
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Summary:Lymphatic filarial nematodes remain a significant cause of morbidity throughout much of the tropics. One approach to the development of rational control methods is an improved understanding of the basic biology of these organisms in relation to the mechanisms used to complete their life cycles. In this article, Eileen Devaney, Sam Martin and Fiona Thompson review new approaches to defining stage-specific molecules in filarial nematodes, and discuss their recent work on the isolation and characterization of stage-regulated cDNAs from Brugia pahangi.
ISSN:0169-4758
1873-1473
DOI:10.1016/0169-4758(96)10065-X