Protein B: An Important Human IgA-binding Reagent

Protein B had a much higher affinity for human IgA than Jacalin, increasing the sensitivity and specificity of the measurement of total human IgA. Protein B, used as a capturing agent, greatly enhanced the measurement of antigen-specific IgA as compared to alpha chain-specific antibodies.

Saved in:
Bibliographic Details
Published in:Annals of the New York Academy of Sciences 1996-02, Vol.778 (1), p.384-387
Main Authors: GRUNDY, M. A., BLAKE, M. S., MURRAY, K.
Format: Article
Language:English
Subjects:
Antibody Specificity
Enzyme-Linked Immunosorbent Assay - methods
Humans
Immunity, Mucosal
Immunoglobulin A - analysis
Immunoglobulin A - metabolism
Interferon Inducers - immunology
Interferon Inducers - metabolism
Kinetics
Lectins - immunology
Lectins - metabolism
Plant Lectins
Protein Binding
Receptors, Fc - metabolism
Sensitivity and Specificity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Protein B had a much higher affinity for human IgA than Jacalin, increasing the sensitivity and specificity of the measurement of total human IgA. Protein B, used as a capturing agent, greatly enhanced the measurement of antigen-specific IgA as compared to alpha chain-specific antibodies.
ISSN:0077-8923
1749-6632
DOI:10.1111/j.1749-6632.1996.tb21151.x