Thromboembolism in a patient with transient eosinophilia

We report here a case of thromboembolism occurring in a 29-year-old woman with transient eosinophilia. Eosinophilia for at least 11 days was followed by pulmonary embolism. Both reperfusion of pulmonary arteries and disappearance of deep vein thrombi were obtained by treatment with urokinase, tissue...

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Bibliographic Details
Published in:Annals of hematology 1996-02, Vol.72 (2), p.93-95
Main Authors: MUKAI, H. Y, NINOMIYA, H, MITSUHASHI, S, HASEGAWA, Y, NAGASAWA, T, ABE, T
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Blood Proteins - secretion
Bronchitis - blood
Bronchitis - complications
Disseminated Intravascular Coagulation - drug therapy
Disseminated Intravascular Coagulation - etiology
Drug Therapy, Combination
Eosinophil Granule Proteins
Eosinophilia - blood
Eosinophilia - complications
Eosinophils - secretion
Female
Hematologic and hematopoietic diseases
Heparin - therapeutic use
Humans
Medical sciences
Other diseases. Hematologic involvement in other diseases
Pulmonary Embolism - drug therapy
Pulmonary Embolism - etiology
Ribonucleases
Thrombophlebitis - drug therapy
Thrombophlebitis - etiology
Tissue Plasminogen Activator - therapeutic use
Urokinase-Type Plasminogen Activator - therapeutic use
Warfarin - therapeutic use
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Summary:We report here a case of thromboembolism occurring in a 29-year-old woman with transient eosinophilia. Eosinophilia for at least 11 days was followed by pulmonary embolism. Both reperfusion of pulmonary arteries and disappearance of deep vein thrombi were obtained by treatment with urokinase, tissue plasminogen activator, and heparin. Although the causes of eosinophilia were not specified, we suggested a causative correlation of elevated serum levels of eosinophil granule proteins with the development of thromboembolism.
ISSN:0939-5555
1432-0584
DOI:10.1007/BF00641316