A Second Double-Stranded RNA Virus from Yeast

Two double-stranded RNA viruses exist as permanent persistent infections of the yeastSaccharomyces cerevisiae:ScVL1 and ScVLa. Both belong to the Totiviridae, which include a number of fungal and protozoan double-stranded RNA viruses. Although ScVL1 and ScVLa share the same genomic organization and...

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Bibliographic Details
Published in:Virology (New York, N.Y.) N.Y.), 1996-02, Vol.216 (2), p.451-454
Main Authors: PARK, CHUNG-MO, LOPINSKI, JOHN D., MASUDA, JENNY, TZENG, TZY-HWA, BRUENN, JEREMY A.
Format: Article
Language:English
Subjects:
ADN
Amino Acid Sequence
ARN
Base Sequence
Capsid - genetics
COMPOSICION QUIMICA
COMPOSITION CHIMIQUE
DNA, Viral - genetics
Genome, Viral
Molecular Sequence Data
Open Reading Frames
PATHOGENESE
PATOGENESIS
RECOMBINACION
RECOMBINAISON
RNA Viruses - genetics
RNA, Double-Stranded - genetics
SACCHAROMYCES CEREVISIAE
Saccharomyces cerevisiae - virology
SECUENCIA NUCLEICA
SEQUENCE NUCLEIQUE
VIRUS DE LAS PLANTAS
VIRUS DES VEGETAUX
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Description
Summary:Two double-stranded RNA viruses exist as permanent persistent infections of the yeastSaccharomyces cerevisiae:ScVL1 and ScVLa. Both belong to the Totiviridae, which include a number of fungal and protozoan double-stranded RNA viruses. Although ScVL1 and ScVLa share the same genomic organization and mode of expression and coexist in the same cells, they show no evidence of recombination: with one limited exception, sequence conservation is detectable only in regions conserved in all totiviruses. Both have two open reading frames on their single essential RNAs:cap(encoding a capsid polypeptide) andpol(encoding an RNA-dependent RNA polymerase). The ScVLa virus, like ScVL1, appears to express its Pol domain by a −1 translational frameshift.
ISSN:0042-6822
1096-0341
DOI:10.1006/viro.1996.0083