V(D)J Recombination and Transposition: Closer Than Expected

V(D)J recombination underlies the ability of the immune system to assemble many different antigen-specific genes from separate gene segments.

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1996-03, Vol.271 (5255), p.1512-1512
Main Author: Craig, Nancy L.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Coding
Deoxyribonucleic acid
DNA
DNA - genetics
DNA - metabolism
DNA Nucleotidyltransferases - metabolism
DNA Transposable Elements
Esterification
Fundamental and applied biological sciences. Psychology
Gene Rearrangement
Gene Rearrangement, T-Lymphocyte
Genes
Genes, Immunoglobulin
Genetic transposition
Genetics
Immunity (Disease)
Immunoglobulin Joining Region - genetics
Immunoglobulin Variable Region - genetics
Microbiology
Molecular Biology
Nucleic Acid Conformation
Perspectives
Recombination, Genetic
VDJ Recombinases
Virology
Virus Integration
Online Access:Get full text
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Description
Summary:V(D)J recombination underlies the ability of the immune system to assemble many different antigen-specific genes from separate gene segments.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.271.5255.1512