Histone Deacetylase: A Regulator of Transcription

One of the major sources of dynamic variation in chromatin structure in vivo is histone acetylation. Rpd3p is a global transcriptional regulator required for target genes to achieve maximal transcriptional efficiency.

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1996-04, Vol.272 (5260), p.371-372
Main Author: Wolffe, Alan P.
Format: Article
Language:English
Subjects:
Acetylation
Allosteric regulation
Biological and medical sciences
Child Health
Chromatin
Chromatin - chemistry
Chromatin - metabolism
DNA
DNA - metabolism
Embryology
Fundamental and applied biological sciences. Psychology
Fungal Proteins - genetics
Fungal Proteins - metabolism
Gene Expression Regulation
Genes
Genetic regulation
Genetic transcription
Genetics
Histone Deacetylases - genetics
Histone Deacetylases - metabolism
Histones
Histones - metabolism
Humans
Individualized Instruction
Literary Devices
Models, Genetic
Molecular and cellular biology
Molecular genetics
Nucleosomes
Perspectives
Regulation
Regulator genes
Repressor Proteins - metabolism
Saccharomyces cerevisiae - genetics
Saccharomyces cerevisiae Proteins
Transcription (Genetics)
Transcription Factors - genetics
Transcription Factors - metabolism
Transcription, Genetic
Transcription. Transcription factor. Splicing. Rna processing
Transcriptional regulatory elements
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Description
Summary:One of the major sources of dynamic variation in chromatin structure in vivo is histone acetylation. Rpd3p is a global transcriptional regulator required for target genes to achieve maximal transcriptional efficiency.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.272.5260.371