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Three-dimensional electrical impedance tomography
THE electrical resistivity of mammalian tissues varies widely 1–5 and is correlated with physiological function 6–8 . Electrical impedance tomography (EIT) can be used to probe such variations in vivo , and offers a non-invasive means of imaging the internal conductivity distribution of the human bo...
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Published in: | Nature (London) 1996-04, Vol.380 (6574), p.509-512 |
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creator | Metherall, P Barber, D. C Smallwood, R. H Brown, B. H |
description | THE electrical resistivity of mammalian tissues varies widely
1–5
and is correlated with physiological function
6–8
. Electrical impedance tomography (EIT) can be used to probe such variations
in vivo
, and offers a non-invasive means of imaging the internal conductivity distribution of the human body
9–11
. But the computational complexity of EIT has severe practical limitations, and previous work has been restricted to considering image reconstruction as an essentially two-dimensional problem
10,12
. This simplification can limit significantly the imaging capabilities of EIT, as the electric currents used to determine the conductivity variations will not in general be confined to a two-dimensional plane
13
. A few studies have attempted three-dimensional EIT image reconstruction
14,15
, but have not yet succeeded in generating images of a quality suitable for clinical applications. Here we report the development of a three-dimensional EIT system with greatly improved imaging capabilities, which combines our 64-electrode data-collection apparatus
16
with customized matrix inversion techniques. Our results demonstrate the practical potential of EIT for clinical applications, such as lung or brain imaging and diagnostic screening
8
. |
doi_str_mv | 10.1038/380509a0 |
format | article |
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1–5
and is correlated with physiological function
6–8
. Electrical impedance tomography (EIT) can be used to probe such variations
in vivo
, and offers a non-invasive means of imaging the internal conductivity distribution of the human body
9–11
. But the computational complexity of EIT has severe practical limitations, and previous work has been restricted to considering image reconstruction as an essentially two-dimensional problem
10,12
. This simplification can limit significantly the imaging capabilities of EIT, as the electric currents used to determine the conductivity variations will not in general be confined to a two-dimensional plane
13
. A few studies have attempted three-dimensional EIT image reconstruction
14,15
, but have not yet succeeded in generating images of a quality suitable for clinical applications. Here we report the development of a three-dimensional EIT system with greatly improved imaging capabilities, which combines our 64-electrode data-collection apparatus
16
with customized matrix inversion techniques. Our results demonstrate the practical potential of EIT for clinical applications, such as lung or brain imaging and diagnostic screening
8
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1–5
and is correlated with physiological function
6–8
. Electrical impedance tomography (EIT) can be used to probe such variations
in vivo
, and offers a non-invasive means of imaging the internal conductivity distribution of the human body
9–11
. But the computational complexity of EIT has severe practical limitations, and previous work has been restricted to considering image reconstruction as an essentially two-dimensional problem
10,12
. This simplification can limit significantly the imaging capabilities of EIT, as the electric currents used to determine the conductivity variations will not in general be confined to a two-dimensional plane
13
. A few studies have attempted three-dimensional EIT image reconstruction
14,15
, but have not yet succeeded in generating images of a quality suitable for clinical applications. Here we report the development of a three-dimensional EIT system with greatly improved imaging capabilities, which combines our 64-electrode data-collection apparatus
16
with customized matrix inversion techniques. Our results demonstrate the practical potential of EIT for clinical applications, such as lung or brain imaging and diagnostic screening
8
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Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Metherall, P</au><au>Barber, D. C</au><au>Smallwood, R. H</au><au>Brown, B. H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Three-dimensional electrical impedance tomography</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1996-04-11</date><risdate>1996</risdate><volume>380</volume><issue>6574</issue><spage>509</spage><epage>512</epage><pages>509-512</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><coden>NATUAS</coden><abstract>THE electrical resistivity of mammalian tissues varies widely
1–5
and is correlated with physiological function
6–8
. Electrical impedance tomography (EIT) can be used to probe such variations
in vivo
, and offers a non-invasive means of imaging the internal conductivity distribution of the human body
9–11
. But the computational complexity of EIT has severe practical limitations, and previous work has been restricted to considering image reconstruction as an essentially two-dimensional problem
10,12
. This simplification can limit significantly the imaging capabilities of EIT, as the electric currents used to determine the conductivity variations will not in general be confined to a two-dimensional plane
13
. A few studies have attempted three-dimensional EIT image reconstruction
14,15
, but have not yet succeeded in generating images of a quality suitable for clinical applications. Here we report the development of a three-dimensional EIT system with greatly improved imaging capabilities, which combines our 64-electrode data-collection apparatus
16
with customized matrix inversion techniques. Our results demonstrate the practical potential of EIT for clinical applications, such as lung or brain imaging and diagnostic screening
8
.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>8606768</pmid><doi>10.1038/380509a0</doi><tpages>4</tpages></addata></record> |
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subjects | Algorithms Biological and medical sciences Computer Simulation Conductivity Electric Impedance Electrical resistivity Humanities and Social Sciences Impedance Investigative techniques, diagnostic techniques (general aspects) letter Medical research Medical sciences Medical screening Miscellaneous. Technology multidisciplinary Radiodiagnosis. Nmr imagery. Nmr spectrometry Science Science (multidisciplinary) Tomography Tomography - methods |
title | Three-dimensional electrical impedance tomography |
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