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QT dispersion in nonsustained ventricular tachycardia and coronary artery disease
This study examines the relation between QT dispersion and the inducibility of ventricular tachycardia (VT) in 35 consecutive patients with coronary artery disease who underwent electrophysiologic testing for evaluation of nonsustained VT. The mean age of the patients was 66 ± 9 years (± SD) and the...
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Published in: | The American journal of cardiology 1996-02, Vol.77 (4), p.256-259 |
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container_title | The American journal of cardiology |
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creator | Bogun, Frank Chan, K.Kwok Harvey, Mark Goyal, Rajiva Castellani, Mark Niebauer, Mark Daoud, Emile Man, K.Ching Strickberger, S.Adam Morady, Fred |
description | This study examines the relation between QT dispersion and the inducibility of ventricular tachycardia (VT) in 35 consecutive patients with coronary artery disease who underwent electrophysiologic testing for evaluation of nonsustained VT. The mean age of the patients was 66 ± 9 years (± SD) and the mean left ventricular ejection fraction was 0.36 ± 0.14. In 6 patients in whom sustained, monomorphic VT was inducible by programmed ventricular stimulation, QT dispersion was significantly greater than in the 29 patients in whom VT was not inducible (126 ± 35 vs 67 ± 25 ms, p < 0.001). All patients who had a QT dispersion >120 ms had inducible sustained monomorphic VT, and no patient who had a QT dispersion |
doi_str_mv | 10.1016/S0002-9149(97)89389-7 |
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The mean age of the patients was 66 ± 9 years (± SD) and the mean left ventricular ejection fraction was 0.36 ± 0.14. In 6 patients in whom sustained, monomorphic VT was inducible by programmed ventricular stimulation, QT dispersion was significantly greater than in the 29 patients in whom VT was not inducible (126 ± 35 vs 67 ± 25 ms, p < 0.001). All patients who had a QT dispersion >120 ms had inducible sustained monomorphic VT, and no patient who had a QT dispersion <90 ms had inducible VT. The patients who had inducible VT did not differ significantly from those who did not with regard to age, gender, ejection fraction, RR interval, or mean QT. In conclusion, in patients with coronary artery disease who have nonsustained VT, inducibility of monomorphic VT is associated with an increase in QT dispersion. QT dispersion may be helpful in predicting which patients with nonsustained VT are and are not likely to have inducible VT by programmed stimulation.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/S0002-9149(97)89389-7</identifier><identifier>PMID: 8607404</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Biological and medical sciences ; Cardiac arrhythmia ; Cardiology. Vascular system ; Cardiovascular disease ; Chi-Square Distribution ; Coronary Disease - complications ; Coronary Disease - physiopathology ; Coronary heart disease ; Electric Stimulation ; Electrocardiography ; Electrophysiology ; Female ; Heart ; Heart Ventricles - physiopathology ; Humans ; Male ; Medical research ; Medical sciences ; Middle Aged ; Regression Analysis ; Tachycardia, Ventricular - etiology ; Tachycardia, Ventricular - physiopathology</subject><ispartof>The American journal of cardiology, 1996-02, Vol.77 (4), p.256-259</ispartof><rights>1995</rights><rights>1996 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. Feb 1, 1996</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c449t-c223baa4b0a8b8f2b4e250013a32127a20594a601518c3ced0f7250c75f24153</citedby><cites>FETCH-LOGICAL-c449t-c223baa4b0a8b8f2b4e250013a32127a20594a601518c3ced0f7250c75f24153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2993767$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8607404$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bogun, Frank</creatorcontrib><creatorcontrib>Chan, K.Kwok</creatorcontrib><creatorcontrib>Harvey, Mark</creatorcontrib><creatorcontrib>Goyal, Rajiva</creatorcontrib><creatorcontrib>Castellani, Mark</creatorcontrib><creatorcontrib>Niebauer, Mark</creatorcontrib><creatorcontrib>Daoud, Emile</creatorcontrib><creatorcontrib>Man, K.Ching</creatorcontrib><creatorcontrib>Strickberger, S.Adam</creatorcontrib><creatorcontrib>Morady, Fred</creatorcontrib><title>QT dispersion in nonsustained ventricular tachycardia and coronary artery disease</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>This study examines the relation between QT dispersion and the inducibility of ventricular tachycardia (VT) in 35 consecutive patients with coronary artery disease who underwent electrophysiologic testing for evaluation of nonsustained VT. The mean age of the patients was 66 ± 9 years (± SD) and the mean left ventricular ejection fraction was 0.36 ± 0.14. In 6 patients in whom sustained, monomorphic VT was inducible by programmed ventricular stimulation, QT dispersion was significantly greater than in the 29 patients in whom VT was not inducible (126 ± 35 vs 67 ± 25 ms, p < 0.001). All patients who had a QT dispersion >120 ms had inducible sustained monomorphic VT, and no patient who had a QT dispersion <90 ms had inducible VT. The patients who had inducible VT did not differ significantly from those who did not with regard to age, gender, ejection fraction, RR interval, or mean QT. In conclusion, in patients with coronary artery disease who have nonsustained VT, inducibility of monomorphic VT is associated with an increase in QT dispersion. QT dispersion may be helpful in predicting which patients with nonsustained VT are and are not likely to have inducible VT by programmed stimulation.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiac arrhythmia</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular disease</subject><subject>Chi-Square Distribution</subject><subject>Coronary Disease - complications</subject><subject>Coronary Disease - physiopathology</subject><subject>Coronary heart disease</subject><subject>Electric Stimulation</subject><subject>Electrocardiography</subject><subject>Electrophysiology</subject><subject>Female</subject><subject>Heart</subject><subject>Heart Ventricles - physiopathology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Regression Analysis</subject><subject>Tachycardia, Ventricular - etiology</subject><subject>Tachycardia, Ventricular - physiopathology</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><recordid>eNqFkE1r3DAQhkVJ2W7S_oSACaGkB7f6smWdQliatLBQlu5djOUxVfBKG8leyL-v9oM95JLTMMwzLzMPIdeMfmeU1T_-Ukp5qZnUd1p9a7RodKk-kDlrlC6ZZuKCzM_IJ3KZ0nNuGavqGZk1NVWSyjlZrdZF59IWY3LBF84XPvg0pRGcx67YoR-js9MAsRjB_nu1EDsHBfiusCEGD_G1gDhiLjkGIeFn8rGHIeGXU70i68ef68Wvcvnn6ffiYVlaKfVYWs5FCyBbCk3b9LyVyKt8nwDBGVfAaaUl1JRVrLHCYkd7lQGrqp5LVokr8vUYu43hZcI0mo1LFocBPIYpGaW05lrtwZs34HOYos-nGS6oqGsh6wxVR8jGkFLE3myj2-TnDKNmr9scdJu9S6OVOeg2Ku9dn8KndoPdeevkN89vT3NIFoY-grcunTGutVD1Pub-iGEWtnMYTbIOff7aRbSj6YJ755D_dvubcQ</recordid><startdate>19960201</startdate><enddate>19960201</enddate><creator>Bogun, Frank</creator><creator>Chan, K.Kwok</creator><creator>Harvey, Mark</creator><creator>Goyal, Rajiva</creator><creator>Castellani, Mark</creator><creator>Niebauer, Mark</creator><creator>Daoud, Emile</creator><creator>Man, K.Ching</creator><creator>Strickberger, S.Adam</creator><creator>Morady, Fred</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19960201</creationdate><title>QT dispersion in nonsustained ventricular tachycardia and coronary artery disease</title><author>Bogun, Frank ; Chan, K.Kwok ; Harvey, Mark ; Goyal, Rajiva ; Castellani, Mark ; Niebauer, Mark ; Daoud, Emile ; Man, K.Ching ; Strickberger, S.Adam ; Morady, Fred</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c449t-c223baa4b0a8b8f2b4e250013a32127a20594a601518c3ced0f7250c75f24153</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cardiac arrhythmia</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular disease</topic><topic>Chi-Square Distribution</topic><topic>Coronary Disease - complications</topic><topic>Coronary Disease - physiopathology</topic><topic>Coronary heart disease</topic><topic>Electric Stimulation</topic><topic>Electrocardiography</topic><topic>Electrophysiology</topic><topic>Female</topic><topic>Heart</topic><topic>Heart Ventricles - physiopathology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Regression Analysis</topic><topic>Tachycardia, Ventricular - etiology</topic><topic>Tachycardia, Ventricular - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bogun, Frank</creatorcontrib><creatorcontrib>Chan, K.Kwok</creatorcontrib><creatorcontrib>Harvey, Mark</creatorcontrib><creatorcontrib>Goyal, Rajiva</creatorcontrib><creatorcontrib>Castellani, Mark</creatorcontrib><creatorcontrib>Niebauer, Mark</creatorcontrib><creatorcontrib>Daoud, Emile</creatorcontrib><creatorcontrib>Man, K.Ching</creatorcontrib><creatorcontrib>Strickberger, S.Adam</creatorcontrib><creatorcontrib>Morady, Fred</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bogun, Frank</au><au>Chan, K.Kwok</au><au>Harvey, Mark</au><au>Goyal, Rajiva</au><au>Castellani, Mark</au><au>Niebauer, Mark</au><au>Daoud, Emile</au><au>Man, K.Ching</au><au>Strickberger, S.Adam</au><au>Morady, Fred</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>QT dispersion in nonsustained ventricular tachycardia and coronary artery disease</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>1996-02-01</date><risdate>1996</risdate><volume>77</volume><issue>4</issue><spage>256</spage><epage>259</epage><pages>256-259</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>This study examines the relation between QT dispersion and the inducibility of ventricular tachycardia (VT) in 35 consecutive patients with coronary artery disease who underwent electrophysiologic testing for evaluation of nonsustained VT. The mean age of the patients was 66 ± 9 years (± SD) and the mean left ventricular ejection fraction was 0.36 ± 0.14. In 6 patients in whom sustained, monomorphic VT was inducible by programmed ventricular stimulation, QT dispersion was significantly greater than in the 29 patients in whom VT was not inducible (126 ± 35 vs 67 ± 25 ms, p < 0.001). All patients who had a QT dispersion >120 ms had inducible sustained monomorphic VT, and no patient who had a QT dispersion <90 ms had inducible VT. The patients who had inducible VT did not differ significantly from those who did not with regard to age, gender, ejection fraction, RR interval, or mean QT. In conclusion, in patients with coronary artery disease who have nonsustained VT, inducibility of monomorphic VT is associated with an increase in QT dispersion. QT dispersion may be helpful in predicting which patients with nonsustained VT are and are not likely to have inducible VT by programmed stimulation.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>8607404</pmid><doi>10.1016/S0002-9149(97)89389-7</doi><tpages>4</tpages></addata></record> |
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subjects | Aged Biological and medical sciences Cardiac arrhythmia Cardiology. Vascular system Cardiovascular disease Chi-Square Distribution Coronary Disease - complications Coronary Disease - physiopathology Coronary heart disease Electric Stimulation Electrocardiography Electrophysiology Female Heart Heart Ventricles - physiopathology Humans Male Medical research Medical sciences Middle Aged Regression Analysis Tachycardia, Ventricular - etiology Tachycardia, Ventricular - physiopathology |
title | QT dispersion in nonsustained ventricular tachycardia and coronary artery disease |
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