Mycosis fungoides presenting as an acquired ichthyosis

A 25-year-old patient with an acquired ichthyosis-like condition is described. Histologic and molecular biologic examination of the fine, whitish, scaling skin lesions suggested the diagnosis of mycosis fungoides. Typical lesions of mycosis fungoides, such as patches, plaques, or tumors, were not pr...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 1996-05, Vol.34 (5), p.887-889
Main Authors: Kütting, Birgitta, Metze, Dieter, Luger, Thomas A., Bonsmann, Gisela
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Diagnosis, Differential
Hematologic and hematopoietic diseases
Humans
Ichthyosis - diagnosis
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Male
Medical sciences
Mycosis Fungoides - diagnosis
Mycosis Fungoides - pathology
Skin Neoplasms - diagnosis
Skin Neoplasms - pathology
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Summary:A 25-year-old patient with an acquired ichthyosis-like condition is described. Histologic and molecular biologic examination of the fine, whitish, scaling skin lesions suggested the diagnosis of mycosis fungoides. Typical lesions of mycosis fungoides, such as patches, plaques, or tumors, were not present. To the best of our knowledge, this is the first case of mycosis fungoides presenting solely with the clinical features of acquired ichthyosis. The sudden appearance of ichthyosiform skin changes in adults must be taken seriously and the underlying cause must be evaluated. A skin biopsy should be performed in all cases of acquired ichthyosis to rule out mycosis fungoides.
ISSN:0190-9622
1097-6787
DOI:10.1016/S0190-9622(96)90072-9