Hemispherectomy and diaschisis: Rapid improvement in cerebral functions after right hemispherectomy in a six year old child

• Published in: Archives of clinical neuropsychology 1988, Vol.3 (1), p.1-8
• Main Authors: Smith, Aaron, Walker, Marion L., Myers, Garth
• Format: Article
• Language: English
• ISSN: 0887-6177; 1873-5843
• DOI: 10.1016/0887-6177(88)90023-6

Neuroradiological, neurological, and neuropsychological studies before and after hemispherectomy for seizures of a six year old boy with left hemiplegia at birth revealed striking postoperative improvement. Seizures ceased and have not recurred. Preoperative EEC studies from seven months of age revealed increasing pathological involvement of the left as well as right hemisphere. Postoperatively, normal tracings over the left hemisphere documented marked and continuing improvement. In contrast to markedly subnormal preoperative WISC-R IQs, retest at 19 months postoperatively showed WISC-R IQs within the normal range, with similar improvement in other tests of cognitive, motor and sensory functions. The arrest and reversal of the preoperative pattern of increasing deterioration and disappearance of pathological involvement of left as well as right hemisphere functions following surgery is consistent with the disappearance of diaschisis as described by von Monakow in 1914, and has conceivably significant clinical as well as theoretical implications.