5-(4-Chlorophenyl)-4-methyl-3-(1-(2- phenylethyl)piperidin-4-yl)isoxazole:  A Potent, Selective Antagonist at Human Cloned Dopamine D4 Receptors

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Bibliographic Details
Published in:Journal of medicinal chemistry 1996-05, Vol.39 (10), p.1943-1945
Main Authors: Rowley, Michael, Broughton, Howard B, Collins, Ian, Baker, Raymond, Emms, Frances, Marwood, Rosemarie, Patel, Shil, Patel, Smita, Ragan, C. Ian, Freedman, Stephen B, Leeson, Paul D
Format: Article
Language:English
Subjects:
Biological and medical sciences
Catecholaminergic system
Cloning, Molecular
Dopamine Antagonists - chemistry
Dopamine Antagonists - pharmacology
Dopamine D2 Receptor Antagonists
Humans
Isoxazoles - chemistry
Isoxazoles - pharmacology
Medical sciences
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
Piperidines - chemistry
Piperidines - pharmacology
Receptors, Dopamine D2 - genetics
Receptors, Dopamine D4
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm960072u