Control of gastrointestinal parasitism in calves with albendazole delivered via an intraruminal controlled-release device

• Published in: Veterinary parasitology 1996-04, Vol.62 (3), p.275-290
• Main Authors: Bell, S.L., Perry, K.W., Rowlinson, P.
• Format: Article
• Language: English
• Subjects: Albendazole; Albendazole - administration & dosage; Albendazole - therapeutic use; Animal Feed; Animals; Anthelmintics - administration & dosage; Anthelmintics - therapeutic use; Cattle; Cattle Diseases; Cattle-Nematoda; Control method-Nematoda; Cooperia spp; Delayed-Action Preparations; Digestive System - parasitology; Feces - parasitology; Female; Gastrins - blood; Growth performance; Housing, Animal; Immunity-Nematoda; Larva; Nematode Infections - prevention & control; Nematode Infections - veterinary; Ostertagia spp; Parasite Egg Count; Rumen; Seasons; Syringes; Time Factors
• ISSN: 0304-4017; 1873-2550
• DOI: 10.1016/0304-4017(95)00872-1

The efficacy of albendazole in an intraruminal controlled-release device against gastrointestinal nematodes in calves was evaluated under field conditions. Calf productivity was monitored during the first and second grazing seasons. Two groups of parasite-naive Holstein Friesian heifer calves were grazed from May to October on adjacent, similarly contaminated paddocks. One group was given a Captec bolus at turnout, the other group was left untreated. Pasture larval counts peaked on the paddock grazed by the untreated calves at 23 000 1 kg −1 dry matter in October. This precipitated clinical parasitic gastro-enteritis in the untreated calves with a mean peak faecal egg count of 335 epg, high blood pepsinogen and gastrin concentrations and a mean worm burden of 79 614 at 100 days post-turnout. Pasture larval counts on the paddock grazed by the treated calves remained less than 3000 1 kg −1 DM and the mean faecal egg count was zero until mid-August, peaking at 146 eggs per gram of faeces (epg) in October. The treated calves had body liveweight advantage of 19 kg at the end of September. During the second grazing season the first season untreated calves were refractory to infection. The first season treated calves showed signs of parasitic gastro-enteritis, although not to the extent exhibited by a group of first season parasite-naive tracer calves which were grazed on the same paddock.