Unusual Breast Masses. The sequential development of mammary tuberculosis and Hodgkin's disease in a young woman

A left breast mass developed in association with pulmonary tuberculosis in a woman 26 years of age. Eight years later, rapidly fatal Hodgkin's Disease with chest wall erosion by involved mediastinal nodes simulating a breast lump developed. Subsequently, a discrete breast mass due to mammary Ho...

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Bibliographic Details
Published in:Cancer 1988-04, Vol.61 (7), p.1457-1459
Main Authors: Graeme‐Cook, Fiona, Sean O'Briain, D., Daly, Peter A.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Biopsy
Breast - pathology
Breast Diseases - genetics
Breast Diseases - pathology
Breast Neoplasms - genetics
Breast Neoplasms - pathology
Female
Gynecology. Andrology. Obstetrics
Hodgkin Disease - genetics
Hodgkin Disease - pathology
Humans
Lymph Nodes - pathology
Mammary gland diseases
Medical sciences
Time Factors
Tuberculosis, Female Genital - genetics
Tuberculosis, Female Genital - pathology
Tumors
Citations: Items that this one cites
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Summary:A left breast mass developed in association with pulmonary tuberculosis in a woman 26 years of age. Eight years later, rapidly fatal Hodgkin's Disease with chest wall erosion by involved mediastinal nodes simulating a breast lump developed. Subsequently, a discrete breast mass due to mammary Hodgkin's disease developed. Involvement of the breast by both tuberculosis and Hodgkin's disease, two diseases often associated with immune dysfunction, in a patient with dysmorphic features and a strong family history of tuberculosis, raises the possibility of an underlying genetic defect. This defect probably involves the immune system.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19880401)61:7<1457::AID-CNCR2820610730>3.0.CO;2-D