Arterial remodeling after coronary angioplasty : A serial intravascular ultrasound study

Restenosis occurs after 30% to 50% of transcatheter coronary procedures; however, the natural history and pathophysiology of restenosis are still incompletely understood. Serial (postintervention and follow-up) intravascular ultrasound imaging was used to study 212 native coronary lesions in 209 pat...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 1996-07, Vol.94 (1), p.35-43
Main Authors: MINTZ, G. S, POPMA, J. J, PICHARD, A. D, KENT, K. M, SATLER, L. F, WONG, S. C, HONG, M. K, KOVACH, J. A, LEON, M. B
Format: Article
Language:English
Subjects:
Aged
Angioplasty, Balloon, Coronary
Arteries - diagnostic imaging
Arteries - physiopathology
Biological and medical sciences
Coronary Disease - diagnostic imaging
Coronary Disease - therapy
Coronary Vessels - diagnostic imaging
Coronary Vessels - physiopathology
Diseases of the cardiovascular system
Female
Humans
Male
Medical sciences
Middle Aged
Postoperative Period
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Recurrence
Ultrasonography, Interventional
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Summary:Restenosis occurs after 30% to 50% of transcatheter coronary procedures; however, the natural history and pathophysiology of restenosis are still incompletely understood. Serial (postintervention and follow-up) intravascular ultrasound imaging was used to study 212 native coronary lesions in 209 patients after percutaneous transluminal coronary angioplasty, directional coronary atherectomy, rotational atherectomy, or excimer laser angioplasty. The external elastic membrane (EEM) and lumen cross-sectional areas (CSA) were measured; plaque plus media (P+M) CSA was calculated as EEM minus lumen CSA. The anatomic slice selected for serial analysis had an axial location within the target lesion at the smallest follow-up lumen CSA. At follow-up, 73% of the decrease in lumen (from 6.6+/-2.5 to 4.0+/-3.7 mm2, P
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.94.1.35