Simulation of intraluminal gas transport processes in the microcirculation

Intraluminal resistance to gas transport between the microcirculation and tissue was neglected for a half-century following the early work of Krogh. In recent years it has come to be understood that this neglect is seriously in error. This paper reviews the background for the long period of misdirec...

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Bibliographic Details
Published in:Annals of biomedical engineering 1996, Vol.24 (1), p.1-24
Main Authors: HELLUMS, J. D, NAIR, P. K, HUANG, N. S, OHSHIMA, N
Format: Article
Language:English
Subjects:
Acid-Base Equilibrium - physiology
Anion Exchange Protein 1, Erythrocyte - metabolism
Biological and medical sciences
Biological Transport
Blood Flow Velocity
Blood-Air Barrier - physiology
Carbon Dioxide - metabolism
Computerized, statistical medical data processing and models in biomedicine
Hematocrit
Humans
Medical sciences
Microcirculation - physiology
Models and simulation
Models, Cardiovascular
Oxygen - metabolism
Vascular Resistance - physiology
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Summary:Intraluminal resistance to gas transport between the microcirculation and tissue was neglected for a half-century following the early work of Krogh. In recent years it has come to be understood that this neglect is seriously in error. This paper reviews the background for the long period of misdirection, and progress in placing the simulation of gas transport processes on a more accurate, quantitative basis.
ISSN:0090-6964
1573-9686