A case of acute pulmonary edema, splenomegaly, and ascites in guinea fowl

• Published in: Avian diseases 1988-01, Vol.32 (1), p.151-156
• Main Authors: Cowen, B.S, Rothenbacher, H, Schwartz, L.D, Braune, M.O, Owen, R.L
• Format: Article
• Language: English
• Subjects: ADENOVIRUS AVIAR; Animals; ASCITE; ASCITES; Ascites - complications; Ascites - pathology; Ascites - veterinary; ASCITIS; AVIADENOVIRUS; BAZO; Bird Diseases - pathology; Birds; Case Reports; Chickens; EDEMA; ENFERMEDADES LINFATICAS; Enteritis; Female; GALLINA DE GUINEA; GUINEA FOWL; Guineafowl; HISTOPATHOLOGY; LUNGS; LYMPHATIC DISEASES; MALADIE DU SYSTEME LYMPHATIQUE; OEDEMA; OEDEME; Pheasants; PINTADE; POUMON; Pulmonary Edema - complications; Pulmonary Edema - pathology; Pulmonary Edema - veterinary; PULMONES; RATE; SPLEEN; Splenic diseases; Splenomegaly; Splenomegaly - complications; Splenomegaly - pathology; Splenomegaly - veterinary; Viruses
• ISSN: 0005-2086; 1938-4351
• DOI: 10.2307/1590966

Acute pulmonary edema, splenomegaly, and ascites were observed in a disease outbreak in adult white and pearl guinea fowl. The clinical history and gross and microscopic lesions resembled those described for marble spleen disease of pheasants and avian adenovirus group II splenomegaly of chickens. A small number of intranuclear inclusion bodies were found in liver, spleen, and lung sections of affected guinea fowl. Attempts to isolate virus and serological tests to detect the presence of viral antigens were unsuccessful. Adult female pearl guinea fowl experimentally exposed to pheasant and turkey isolates of type II avian adenoviruses developed gross and microscopic lesions similar to those seen in the field outbreak. The pheasant isolate was the more virulent. Intranuclear inclusion bodies were observed in liver, spleen, and lung sections of pearl guinea fowl inoculated with either of the virus isolates, and direct immunoflurescent examination revealed viral antigen in the spleen and lung. /// Se presentó un brote con edema pulmonar agudo, esplenomegalia y ascitis en gallinas de Guinea adultas blancas y pintadas. La historia clínica y las lesiones macro y microscópicas fueron semejantes a las observadas en la enfermedad del bazo moteado de faisanes y la esplenomegalia causada por adenovirus aviar grupo II en pollos. Se encontró un número pequeño de cuerpos de inclusión intranucleares en secciones de hígado, bazo y pulmón. No fructificaron los intentos para aislar el virus o para identificar los antígenos virales por medio de las pruebas serológicas. Gallinas de Guinea pintadas expuestas experimentalmente a cepas del tipo II de adenovirus de faisán y pollo desarrollaron lesiones macro y microscópicas similares a las observadas en el brote de campo, siendo la cepa de faisán la más virulenta. Se encontraron cuerpos de inclusión intranucleares en secciones de hígado, bazo y pulmón de gallinas de Guinea pintadas inoculadas con cualquiera de las cepas y el examen por inmunofluorescencia directa identificó el antígeno viral en bazo y pulmón.