Primary non-Hodgkin malignant lymphoma of the male breast

A case of primary non-Hodgkin lymphoma of the male breast is reported. The patient was a 76-year-old Japanese with a history of bilateral gynecomastia. After the patient had received sex hormone treatment for the gynecomastia, rapid growth of a tumor in the right breast was noted, with regression of...

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Bibliographic Details
Published in:Japanese journal of clinical oncology 1996-08, Vol.26 (4), p.243-247
Main Authors: Murata, T, Kuroda, H, Nakahama, T, Goshima, H, Shiraishi, T, Yatani, R
Format: Article
Language:English
Subjects:
Aged
Breast Neoplasms, Male - diagnosis
Breast Neoplasms, Male - pathology
Breast Neoplasms, Male - therapy
Combined Modality Therapy
Humans
Immunohistochemistry
Lymphoma, B-Cell - diagnosis
Lymphoma, B-Cell - pathology
Lymphoma, B-Cell - therapy
Lymphoma, Large B-Cell, Diffuse - diagnosis
Lymphoma, Large B-Cell, Diffuse - pathology
Lymphoma, Large B-Cell, Diffuse - therapy
Male
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Summary:A case of primary non-Hodgkin lymphoma of the male breast is reported. The patient was a 76-year-old Japanese with a history of bilateral gynecomastia. After the patient had received sex hormone treatment for the gynecomastia, rapid growth of a tumor in the right breast was noted, with regression of a contralateral breast lesion. Clinically, inflammatory breast cancer was suspected, and right mastectomy with ipsilateral axillary lymph node dissection was performed after intraarterial infusion chemotherapy using a cis-platinum derivative. The histology of the surgical specimen was non-Hodgkin malignant lymphoma of the diffuse large cell type, with focal tumor necrosis. Immunohistochemically, the tumor cells showed a B-cell nature. The patient is currently well without disease 39 months after surgery.
ISSN:0368-2811
1465-3621
DOI:10.1093/oxfordjournals.jjco.a023222