Spontaneous Coronary Artery Spasm Documented in a Young Woman: A Case Report

A 35-year-old woman with coronary risk factors presented with nonexertional atypical burning chest pain of 1 week's duration. A myocardial perfusion study with Tc-99m MIBI revealed a severe stress induced anteroseptal perfusion defect that completely reperfused on a subsequent resting Tc-99m MI...

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Bibliographic Details
Published in:Clinical nuclear medicine 1996-06, Vol.21 (6), p.452-455
Main Authors: CAMPEAU, RICHARD J, SPELLMAN, JOHN G, TENAGLIA, ALAN N
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Cardiovascular system
Coronary Angiography
Coronary Vasospasm - diagnostic imaging
Exercise Test
Female
Heart - diagnostic imaging
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Radionuclide investigations
Technetium Tc 99m Sestamibi
Tomography, Emission-Computed, Single-Photon
Citations: Items that this one cites
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Summary:A 35-year-old woman with coronary risk factors presented with nonexertional atypical burning chest pain of 1 week's duration. A myocardial perfusion study with Tc-99m MIBI revealed a severe stress induced anteroseptal perfusion defect that completely reperfused on a subsequent resting Tc-99m MIBI study. Coronary angiography showed mild nonobstructive coronary artery disease. At the termination of the procedure, a spontaneous episode of burning chest pain occurred. Left main coronary artery reinjection of contrast revealed proximal diffuse left anterior descending coronary artery spasm. The patient was followed for 2 years with no further episodes of chest pain, while on calcium channel-blocker medication. The phenomenon of vasospastic angina and the role of myocardial perfusion scintigraphy is discussed.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199606000-00003