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Hypertonic hemolysis in patients with a mood disorder
Hypertonic hemolysis was increased in patients with a manic episode ( n = 6, mean NaCl concentration in mol/L at which 50% of the erythrocytes was hemolyzed (H 50) 3.24 ± 0.10), compared to healthy controls ( n = 12, mean H 50 3.43 ± 0.13) ( p ≤ 0.02) and patients with a nonaffective psychotic disor...
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| Published in: | Biological psychiatry (1969) 1996, Vol.39 (1), p.11-15 |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c386t-e11f20d33043ce01e4799a3c898aa8737d4c5e738db17840a7450da715d28e2b3 |
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| cites | cdi_FETCH-LOGICAL-c386t-e11f20d33043ce01e4799a3c898aa8737d4c5e738db17840a7450da715d28e2b3 |
| container_end_page | 15 |
| container_issue | 1 |
| container_start_page | 11 |
| container_title | Biological psychiatry (1969) |
| container_volume | 39 |
| creator | Hoeksema, Ton Goekoop, Jaap G. Van Kempen, Godfried M.J. |
| description | Hypertonic hemolysis was increased in patients with a manic episode (
n = 6, mean NaCl concentration in mol/L at which 50% of the erythrocytes was hemolyzed (H
50) 3.24 ± 0.10), compared to healthy controls (
n = 12, mean H
50 3.43 ± 0.13) (
p ≤ 0.02) and patients with a nonaffective psychotic disorder (
n = 15, mean H
50 3.42 ± 0.18) (
p ≤ 0.02). Compared to these two control groups, hypertonic hemolysis was decreased in patients with a severe depressive episode (
n = 8, mean H
50 3.62 ± 0.19) (
p ≤ 0.05 and
p ≤ 0.02, respectively). Within the total depressed patient group, the patients with an increased genetic vulnerability (
n = 8, mean H
50 3.68 ± 0.16) showed a decreased hypertonic hemolysis compared to the other depressed patients (
n = 14, mean H
50 3.40 ± 0.16) (
p ≤ 0.002). |
| doi_str_mv | 10.1016/0006-3223(95)00106-9 |
| format | article |
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n = 6, mean NaCl concentration in mol/L at which 50% of the erythrocytes was hemolyzed (H
50) 3.24 ± 0.10), compared to healthy controls (
n = 12, mean H
50 3.43 ± 0.13) (
p ≤ 0.02) and patients with a nonaffective psychotic disorder (
n = 15, mean H
50 3.42 ± 0.18) (
p ≤ 0.02). Compared to these two control groups, hypertonic hemolysis was decreased in patients with a severe depressive episode (
n = 8, mean H
50 3.62 ± 0.19) (
p ≤ 0.05 and
p ≤ 0.02, respectively). Within the total depressed patient group, the patients with an increased genetic vulnerability (
n = 8, mean H
50 3.68 ± 0.16) showed a decreased hypertonic hemolysis compared to the other depressed patients (
n = 14, mean H
50 3.40 ± 0.16) (
p ≤ 0.002).</description><identifier>ISSN: 0006-3223</identifier><identifier>EISSN: 1873-2402</identifier><identifier>DOI: 10.1016/0006-3223(95)00106-9</identifier><identifier>PMID: 8719120</identifier><identifier>CODEN: BIPCBF</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Adult and adolescent clinical studies ; Aged ; Biological and medical sciences ; Bipolar Disorder - blood ; Bipolar Disorder - genetics ; Depressive Disorder - blood ; Depressive Disorder - genetics ; Erythrocytes ; Female ; hemolysis ; Hemolysis - genetics ; Hemolysis - physiology ; Humans ; Male ; Mania ; Medical sciences ; Middle Aged ; Mood disorders ; Osmotic Fragility - genetics ; Osmotic Fragility - physiology ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Risk Factors</subject><ispartof>Biological psychiatry (1969), 1996, Vol.39 (1), p.11-15</ispartof><rights>1996 Society of Biological Psychiatry</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-e11f20d33043ce01e4799a3c898aa8737d4c5e738db17840a7450da715d28e2b3</citedby><cites>FETCH-LOGICAL-c386t-e11f20d33043ce01e4799a3c898aa8737d4c5e738db17840a7450da715d28e2b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2987271$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8719120$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hoeksema, Ton</creatorcontrib><creatorcontrib>Goekoop, Jaap G.</creatorcontrib><creatorcontrib>Van Kempen, Godfried M.J.</creatorcontrib><title>Hypertonic hemolysis in patients with a mood disorder</title><title>Biological psychiatry (1969)</title><addtitle>Biol Psychiatry</addtitle><description>Hypertonic hemolysis was increased in patients with a manic episode (
n = 6, mean NaCl concentration in mol/L at which 50% of the erythrocytes was hemolyzed (H
50) 3.24 ± 0.10), compared to healthy controls (
n = 12, mean H
50 3.43 ± 0.13) (
p ≤ 0.02) and patients with a nonaffective psychotic disorder (
n = 15, mean H
50 3.42 ± 0.18) (
p ≤ 0.02). Compared to these two control groups, hypertonic hemolysis was decreased in patients with a severe depressive episode (
n = 8, mean H
50 3.62 ± 0.19) (
p ≤ 0.05 and
p ≤ 0.02, respectively). Within the total depressed patient group, the patients with an increased genetic vulnerability (
n = 8, mean H
50 3.68 ± 0.16) showed a decreased hypertonic hemolysis compared to the other depressed patients (
n = 14, mean H
50 3.40 ± 0.16) (
p ≤ 0.002).</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Bipolar Disorder - blood</subject><subject>Bipolar Disorder - genetics</subject><subject>Depressive Disorder - blood</subject><subject>Depressive Disorder - genetics</subject><subject>Erythrocytes</subject><subject>Female</subject><subject>hemolysis</subject><subject>Hemolysis - genetics</subject><subject>Hemolysis - physiology</subject><subject>Humans</subject><subject>Male</subject><subject>Mania</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mood disorders</subject><subject>Osmotic Fragility - genetics</subject><subject>Osmotic Fragility - physiology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Risk Factors</subject><issn>0006-3223</issn><issn>1873-2402</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LxDAQhoMo67r6DxR6ENFDNR9tk1wEWdQVFrzoOWSTKUbaZk26yv57U7fs0dMwzDMzLw9C5wTfEkyqO4xxlTNK2bUsbzAmqZMHaEoEZzktMD1E0z1yjE5i_Ewtp5RM0ERwIgnFU1QutmsIve-cyT6g9c02upi5Llvr3kHXx-zH9R-ZzlrvbWZd9MFCOEVHtW4inI11ht6fHt_mi3z5-vwyf1jmhomqz4GQmmLLGC6YAUyg4FJqZoQUWqeY3BamBM6EXREuCqx5UWKrOSktFUBXbIaudnfXwX9tIPaqddFA0-gO_CYqLiivsCAJLHagCT7GALVaB9fqsFUEq8GWGlSoQYWSpfqzpWRauxjvb1Yt2P3SqCfNL8e5jkY3ddCdcXGPUSk45cP3-x0GycW3g6CiSfIMWBfA9Mp693-OXzvWg-o</recordid><startdate>1996</startdate><enddate>1996</enddate><creator>Hoeksema, Ton</creator><creator>Goekoop, Jaap G.</creator><creator>Van Kempen, Godfried M.J.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1996</creationdate><title>Hypertonic hemolysis in patients with a mood disorder</title><author>Hoeksema, Ton ; Goekoop, Jaap G. ; Van Kempen, Godfried M.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-e11f20d33043ce01e4799a3c898aa8737d4c5e738db17840a7450da715d28e2b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Bipolar Disorder - blood</topic><topic>Bipolar Disorder - genetics</topic><topic>Depressive Disorder - blood</topic><topic>Depressive Disorder - genetics</topic><topic>Erythrocytes</topic><topic>Female</topic><topic>hemolysis</topic><topic>Hemolysis - genetics</topic><topic>Hemolysis - physiology</topic><topic>Humans</topic><topic>Male</topic><topic>Mania</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mood disorders</topic><topic>Osmotic Fragility - genetics</topic><topic>Osmotic Fragility - physiology</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hoeksema, Ton</creatorcontrib><creatorcontrib>Goekoop, Jaap G.</creatorcontrib><creatorcontrib>Van Kempen, Godfried M.J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Biological psychiatry (1969)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hoeksema, Ton</au><au>Goekoop, Jaap G.</au><au>Van Kempen, Godfried M.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hypertonic hemolysis in patients with a mood disorder</atitle><jtitle>Biological psychiatry (1969)</jtitle><addtitle>Biol Psychiatry</addtitle><date>1996</date><risdate>1996</risdate><volume>39</volume><issue>1</issue><spage>11</spage><epage>15</epage><pages>11-15</pages><issn>0006-3223</issn><eissn>1873-2402</eissn><coden>BIPCBF</coden><abstract>Hypertonic hemolysis was increased in patients with a manic episode (
n = 6, mean NaCl concentration in mol/L at which 50% of the erythrocytes was hemolyzed (H
50) 3.24 ± 0.10), compared to healthy controls (
n = 12, mean H
50 3.43 ± 0.13) (
p ≤ 0.02) and patients with a nonaffective psychotic disorder (
n = 15, mean H
50 3.42 ± 0.18) (
p ≤ 0.02). Compared to these two control groups, hypertonic hemolysis was decreased in patients with a severe depressive episode (
n = 8, mean H
50 3.62 ± 0.19) (
p ≤ 0.05 and
p ≤ 0.02, respectively). Within the total depressed patient group, the patients with an increased genetic vulnerability (
n = 8, mean H
50 3.68 ± 0.16) showed a decreased hypertonic hemolysis compared to the other depressed patients (
n = 14, mean H
50 3.40 ± 0.16) (
p ≤ 0.002).</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>8719120</pmid><doi>10.1016/0006-3223(95)00106-9</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Biological psychiatry (1969), 1996, Vol.39 (1), p.11-15 |
| issn | 0006-3223 1873-2402 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78276081 |
| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | Adolescent Adult Adult and adolescent clinical studies Aged Biological and medical sciences Bipolar Disorder - blood Bipolar Disorder - genetics Depressive Disorder - blood Depressive Disorder - genetics Erythrocytes Female hemolysis Hemolysis - genetics Hemolysis - physiology Humans Male Mania Medical sciences Middle Aged Mood disorders Osmotic Fragility - genetics Osmotic Fragility - physiology Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Risk Factors |
| title | Hypertonic hemolysis in patients with a mood disorder |
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