Spinal cord ependymoma : a positron emission tomographic study with (11C-methyl)-L-methionine

An intramedullary spinal cord ependymoma was studied by positron emission tomography (PET) using (11C-methyl)-L-methionine (11C-Met). MRI showed a homogeneously enhancing tumour at C6-T2 with cysts at its rostral and caudal ends. Sagittal PET images demonstrated high 11C-Met uptake in the solid port...

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Bibliographic Details
Published in:Neuroradiology 1996, Vol.38 (1), p.53-55
Main Authors: SASAJIMA, T, MINEURA, K, ITOH, Y, KOWADA, M, HATAZAWA, J, OGAWA, T, UEMURA, K
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Carbon Radioisotopes - pharmacokinetics
Ependymoma - diagnostic imaging
Ependymoma - pathology
Ependymoma - surgery
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Methionine - analogs & derivatives
Methionine - pharmacokinetics
Nervous system
Radionuclide investigations
Spinal Cord - diagnostic imaging
Spinal Cord - pathology
Spinal Cord - surgery
Spinal Cord Neoplasms - diagnostic imaging
Spinal Cord Neoplasms - pathology
Spinal Cord Neoplasms - surgery
Tissue Survival - physiology
Tomography, Emission-Computed
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Summary:An intramedullary spinal cord ependymoma was studied by positron emission tomography (PET) using (11C-methyl)-L-methionine (11C-Met). MRI showed a homogeneously enhancing tumour at C6-T2 with cysts at its rostral and caudal ends. Sagittal PET images demonstrated high 11C-Met uptake in the solid portion of the tumour, particularly ventrally at C7-T2, where viable tumour cells proliferated in association with abundant perforating vessels. Met-PET would appear useful for delineating the viable portion of intramedullary ependymomas.
ISSN:0028-3940
1432-1920
DOI:10.1007/BF00593221