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Correlation between Colposcopically Directed Biopsy and Cervical Loop Excision
Colpscopy is standard for diagnosis of cervical cancer precursors, but the development of diathermy loop electrodes for excision of the cervical transformation zone offers a technique for validation. Loop excision of the transformation zone was performed for 47 consecutive women with dysplasia in co...
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Published in: | Gynecologic oncology 1996-03, Vol.60 (3), p.400-403 |
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container_title | Gynecologic oncology |
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creator | Massad, L.Stewart Halperin, Cathy J. Bitterman, Pincas |
description | Colpscopy is standard for diagnosis of cervical cancer precursors, but the development of diathermy loop electrodes for excision of the cervical transformation zone offers a technique for validation. Loop excision of the transformation zone was performed for 47 consecutive women with dysplasia in colposcopically directed biopsies using 20 × 8-mm electrodes. Specimens were marked for orientation and serially sectioned. All pathology material was reviewed. Although 28% of women had disappearance of dysplasia at the biopsy site, only 9% had no dysplasia in the transformation zone. Half of the women with CIN 1 on directed biopsy had high-grade lesions found in loop excision specimens. Significant discrepancies may be found between the results of colposcopically directed biopsy and loop excision. |
doi_str_mv | 10.1006/gyno.1996.0062 |
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Loop excision of the transformation zone was performed for 47 consecutive women with dysplasia in colposcopically directed biopsies using 20 × 8-mm electrodes. Specimens were marked for orientation and serially sectioned. All pathology material was reviewed. Although 28% of women had disappearance of dysplasia at the biopsy site, only 9% had no dysplasia in the transformation zone. Half of the women with CIN 1 on directed biopsy had high-grade lesions found in loop excision specimens. Significant discrepancies may be found between the results of colposcopically directed biopsy and loop excision.</description><identifier>ISSN: 0090-8258</identifier><identifier>EISSN: 1095-6859</identifier><identifier>DOI: 10.1006/gyno.1996.0062</identifier><identifier>PMID: 8774646</identifier><identifier>CODEN: GYNOA3</identifier><language>eng</language><publisher>San Diego, CA: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Biopsy - methods ; Cervical Intraepithelial Neoplasia - pathology ; Cervix Uteri - pathology ; Cervix Uteri - surgery ; Colposcopy ; Diathermy ; Female ; Female genital diseases ; Gynecology. Andrology. 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Loop excision of the transformation zone was performed for 47 consecutive women with dysplasia in colposcopically directed biopsies using 20 × 8-mm electrodes. Specimens were marked for orientation and serially sectioned. All pathology material was reviewed. Although 28% of women had disappearance of dysplasia at the biopsy site, only 9% had no dysplasia in the transformation zone. Half of the women with CIN 1 on directed biopsy had high-grade lesions found in loop excision specimens. Significant discrepancies may be found between the results of colposcopically directed biopsy and loop excision.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Biopsy - methods</subject><subject>Cervical Intraepithelial Neoplasia - pathology</subject><subject>Cervix Uteri - pathology</subject><subject>Cervix Uteri - surgery</subject><subject>Colposcopy</subject><subject>Diathermy</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Radiosurgery</subject><subject>Tumors</subject><subject>Uterine Cervical Dysplasia - pathology</subject><subject>Uterine Cervical Neoplasms - pathology</subject><issn>0090-8258</issn><issn>1095-6859</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><recordid>eNp1kEtLxDAURoMoOj627oQuxF3Hmz7SZKn1CYNudB2S9FYinaYmHXX-vakzuBMCIXwnH_ceQk4pzCkAu3xb925OhWDz-Mp2yIyCKFPGS7FLZgACUp6V_IAchvAOADnQbJ_s86oqWMFm5Kl23mOnRuv6ROP4hdgntesGF4wbrFFdt05urEczYpNcWzeEdaL6JqnRf05xsnBuSG6_jQ2x4pjstaoLeLK9j8jr3e1L_ZAunu8f66tFanLGx5QyxcA0bUmbvGhFZVoBpTaGGqOUhrKKJ8sLUVWZZlQVmitAJoTKtdGaZfkRudj0Dt59rDCMcmmDwa5TPbpVkBXPeA4FjeB8AxrvQvDYysHbpfJrSUFOAuUkUE4C5SQwfjjbNq_0Eps_fGss5ufbXIW4futVH1f_w6JfyEBEjG8wjBY-LXoZjMXeYPPrUjbO_jfBDyOtjNM</recordid><startdate>19960301</startdate><enddate>19960301</enddate><creator>Massad, L.Stewart</creator><creator>Halperin, Cathy J.</creator><creator>Bitterman, Pincas</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19960301</creationdate><title>Correlation between Colposcopically Directed Biopsy and Cervical Loop Excision</title><author>Massad, L.Stewart ; Halperin, Cathy J. ; Bitterman, Pincas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c368t-16a60cdf51d34f97cf905bcc1ccaab0570572349772b61a4b8a0e699a3bcbb623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Biopsy - methods</topic><topic>Cervical Intraepithelial Neoplasia - pathology</topic><topic>Cervix Uteri - pathology</topic><topic>Cervix Uteri - surgery</topic><topic>Colposcopy</topic><topic>Diathermy</topic><topic>Female</topic><topic>Female genital diseases</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Radiosurgery</topic><topic>Tumors</topic><topic>Uterine Cervical Dysplasia - pathology</topic><topic>Uterine Cervical Neoplasms - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Massad, L.Stewart</creatorcontrib><creatorcontrib>Halperin, Cathy J.</creatorcontrib><creatorcontrib>Bitterman, Pincas</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Gynecologic oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Massad, L.Stewart</au><au>Halperin, Cathy J.</au><au>Bitterman, Pincas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Correlation between Colposcopically Directed Biopsy and Cervical Loop Excision</atitle><jtitle>Gynecologic oncology</jtitle><addtitle>Gynecol Oncol</addtitle><date>1996-03-01</date><risdate>1996</risdate><volume>60</volume><issue>3</issue><spage>400</spage><epage>403</epage><pages>400-403</pages><issn>0090-8258</issn><eissn>1095-6859</eissn><coden>GYNOA3</coden><abstract>Colpscopy is standard for diagnosis of cervical cancer precursors, but the development of diathermy loop electrodes for excision of the cervical transformation zone offers a technique for validation. Loop excision of the transformation zone was performed for 47 consecutive women with dysplasia in colposcopically directed biopsies using 20 × 8-mm electrodes. Specimens were marked for orientation and serially sectioned. All pathology material was reviewed. Although 28% of women had disappearance of dysplasia at the biopsy site, only 9% had no dysplasia in the transformation zone. Half of the women with CIN 1 on directed biopsy had high-grade lesions found in loop excision specimens. Significant discrepancies may be found between the results of colposcopically directed biopsy and loop excision.</abstract><cop>San Diego, CA</cop><pub>Elsevier Inc</pub><pmid>8774646</pmid><doi>10.1006/gyno.1996.0062</doi><tpages>4</tpages></addata></record> |
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source | ScienceDirect Journals |
subjects | Adult Biological and medical sciences Biopsy - methods Cervical Intraepithelial Neoplasia - pathology Cervix Uteri - pathology Cervix Uteri - surgery Colposcopy Diathermy Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Medical sciences Radiosurgery Tumors Uterine Cervical Dysplasia - pathology Uterine Cervical Neoplasms - pathology |
title | Correlation between Colposcopically Directed Biopsy and Cervical Loop Excision |
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