An early detection program for respiratory insufficiency in Duchenne's disease: the preliminary results

Noninvasive mechanical ventilation through a nasal mask is a recently introduced therapeutic tool that represents a noteworthy advance in home treatment for patients with respiratory insufficiency secondary to ventilatory pump failure. We present the preliminary results of a program for early detect...

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Bibliographic Details
Published in:Archivos de bronconeumología 1996-06, Vol.32 (6), p.267-270
Main Authors: Díaz Lobato, S, Gómez de Terreros, F J, García Tejero, M T, Corral, J, Vázquez, C, Redondo, M A, Echavarri, C, Martínez, J, Villasante, C
Format: Article
Language:Spanish
Subjects:
Adolescent
Child
Home Care Services
Humans
Male
Masks
Muscular Dystrophies - complications
Muscular Dystrophies - therapy
Respiration, Artificial
Respiratory Function Tests - statistics & numerical data
Respiratory Insufficiency - diagnosis
Respiratory Insufficiency - etiology
Respiratory Insufficiency - therapy
Time Factors
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Summary:Noninvasive mechanical ventilation through a nasal mask is a recently introduced therapeutic tool that represents a noteworthy advance in home treatment for patients with respiratory insufficiency secondary to ventilatory pump failure. We present the preliminary results of a program for early detection of respiratory insufficiency in patients with Duchenne's disease. Sixteen patients (mean age 15.8 years) with this disease were evaluated between January 1994 and January 1995. Mean lung function parameters were FVC 1,440 ml (46.7%), PO2 87.3 mmHg, PCO2 40.8 mmHg, PIM 40.1 cmH2O (30.6%), and PEM 41 cmH2O (25%). Two patients had abnormal pulse oximetry readings at night and abnormal gasometric readings during the day and were started on mechanical ventilation through nasal masks. These 2 patients were older, more hypoxemic and hypercapnic, had lower FVC values and showed greater deterioration of inspiratory and expiratory muscle pressures.
ISSN:0300-2896