Vasoactive Intestinal Peptide in Sepsis and Shock

Large amounts of VIP-containing neurons are located in the gastrointestinal tract. VIP, which harbors potent vasodilatory effects, could be one of the connections between the classical neural and hormonal systems. In order to evaluate the possible role of VIP in sepsis and shock in general, the auth...

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Bibliographic Details
Published in:Annals of the New York Academy of Sciences 1988, Vol.527 (1), p.536-545
Main Authors: REVHAUG, ARTHUR, LYGREN, IDAR, JENSSEN, TROND G., GIERCKSKY, KARL-E., BURHOL, PER G.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Blood Pressure
Cardiac Output
Endocrinopathies
Escherichia coli
General aspects. Associated endocrine diseases. Endocrine paraneoplasic syndromes
Humans
Kinetics
Lipopolysaccharides
Medical sciences
Shock, Hemorrhagic - physiopathology
Shock, Septic - etiology
Shock, Septic - physiopathology
Swine
Vascular Resistance
Vasoactive Intestinal Peptide - blood
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Summary:Large amounts of VIP-containing neurons are located in the gastrointestinal tract. VIP, which harbors potent vasodilatory effects, could be one of the connections between the classical neural and hormonal systems. In order to evaluate the possible role of VIP in sepsis and shock in general, the authors tried to elucidate if--and eventually how--VIP is involved in shock states.
ISSN:0077-8923
1749-6632
DOI:10.1111/j.1749-6632.1988.tb27007.x