The Role of Vasoactive Intestinal Peptide and Other Neuropeptides in the Regulation of the Immune Response in Vitro and in Vivo

In this report the authors review observations concerning the effects of VIP on immune responses and compare them to those of other neuropeptides. They have been particularly interested in substance P (SP) and somatostatin (SOM) since these substances, similar to VIP, are found in high concentration...

Full description

Saved in:
Bibliographic Details
Published in:Annals of the New York Academy of Sciences 1988, Vol.527 (1), p.478-485
Main Authors: STANISZ, ANDRZEJ M., SCICCHITANO, RAFFAELE, BIENENSTOCK, JOHN
Format: Article
Language:English
Subjects:
Animals
Apud cells. Peptide and protein hormones. Growth factors
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Humans
Immunity - drug effects
Immunoglobulins - biosynthesis
Lymphocyte Activation
Neuropeptides - pharmacology
Neuropeptides - physiology
Vasoactive Intestinal Peptide - pharmacology
Vasoactive Intestinal Peptide - physiology
Vertebrates: endocrinology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this report the authors review observations concerning the effects of VIP on immune responses and compare them to those of other neuropeptides. They have been particularly interested in substance P (SP) and somatostatin (SOM) since these substances, similar to VIP, are found in high concentrations in mucosal tissues where they are thought to act primarily as neurotransmitters, although there is increasing evidence that they act as local immunomodulators.
ISSN:0077-8923
1749-6632
DOI:10.1111/j.1749-6632.1988.tb27001.x