Internalization of Escherichia coli into Human Renal Tubular Epithelial Cells

The authors report here that stains of Escherichia coli , the most common cause of acute pyelonephritis, are internalized into human renal proximal tubular epithelial cells and are frequently enclosed in membrane-bound vacuoles, a finding suggesting that a process similar to phagocytosis has taken p...

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Bibliographic Details
Published in:The Journal of infectious diseases 1988-07, Vol.158 (1), p.221-223
Main Authors: Warren, John W., Mobley, Harry L. T., Thifillis, Anna L.
Format: Article
Language:English
Subjects:
Adult
Bacteria
Bacterial Adhesion
Bacteriology
Biological and medical sciences
Concise Clinical and Laboratory Communications
Endocytosis
Epithelial cells
Epithelium
Epithelium - microbiology
Escherichia coli
Escherichia coli - isolation & purification
Escherichia coli Infections - microbiology
Female
Fundamental and applied biological sciences. Psychology
Humans
Infections
Kidney Tubules, Proximal - microbiology
Microbiology
Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains
Pathology
Phagocytosis
Pyelonephritis
Pyelonephritis - microbiology
Ruthenium
Urinary tract
Vacuoles
Vacuoles - microbiology
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Description
Summary:The authors report here that stains of Escherichia coli , the most common cause of acute pyelonephritis, are internalized into human renal proximal tubular epithelial cells and are frequently enclosed in membrane-bound vacuoles, a finding suggesting that a process similar to phagocytosis has taken place.
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/158.1.221