Multifocal white matter lesions

There is a long differential diagnosis for multifocal white matter lesions on MR. The most common causes are prominent Virchow-Robin spaces, white matter ischemic change, and multiple sclerosis, but many other causes have been reported. Most of these are related to vascular or other demyelinating et...

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Bibliographic Details
Published in:Seminars in ultrasound, CT, and MRI CT, and MRI, 1996-06, Vol.17 (3), p.251-264
Main Authors: Wallace, Carla J, Sevick, Robert J
Format: Article
Language:English
Subjects:
Brain Diseases - diagnosis
Brain Injuries - diagnosis
Brain Ischemia - diagnosis
Brain Neoplasms - diagnosis
Cerebrovascular Disorders - diagnosis
Demyelinating Diseases - diagnosis
Diagnosis, Differential
Encephalitis - diagnosis
Humans
Infection
Magnetic Resonance Imaging
Multiple Sclerosis - diagnosis
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Summary:There is a long differential diagnosis for multifocal white matter lesions on MR. The most common causes are prominent Virchow-Robin spaces, white matter ischemic change, and multiple sclerosis, but many other causes have been reported. Most of these are related to vascular or other demyelinating etiologies, but infectious/inflammatory disease, trauma, and neoplastic and other unusual causes may also be responsible. Typical imaging features of the more common multifocal white matter disorders are outlined, and the rarer causes are discussed briefly. An approach to imaging differential diagnosis is given, with emphasis on the differences between white matter ischemic lesions and multiple sclerosis.
ISSN:0887-2171
1558-5034
DOI:10.1016/S0887-2171(96)90038-4