Chromosomal mapping of cell death proteases CPP32, MCH2, and MCH3

Apoptosis may involve a specialized proteolytic cascade catalyzed by interleukin-1beta-converting enzyme-like proteases. We have recently identified three new members of this family (CPP32, MCH2, MCH3) and shown that they play an important role in promoting cell death. Here we report the chromosomal...

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Bibliographic Details
Published in:Genomics (San Diego, Calif.) Calif.), 1996-09, Vol.36 (2), p.362-365
Main Authors: BULLRICH, F, FERNANDES-ALNEMRI, T, LITWACK, G, ALNEMRI, E. S, CROCE, C. M
Format: Article
Language:English
Subjects:
Animals
Apoptosis
Biological and medical sciences
Caspase 1
Caspase 3
Caspases
Chromosome Mapping
Chromosomes, Human, Pair 10
Chromosomes, Human, Pair 4
Classical genetics, quantitative genetics, hybrids
Cysteine Endopeptidases - genetics
Fundamental and applied biological sciences. Psychology
Genetics of eukaryotes. Biological and molecular evolution
Human
Humans
Rodentia
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Summary:Apoptosis may involve a specialized proteolytic cascade catalyzed by interleukin-1beta-converting enzyme-like proteases. We have recently identified three new members of this family (CPP32, MCH2, MCH3) and shown that they play an important role in promoting cell death. Here we report the chromosomal mapping of CPP32 to 4q34, MCH2 to 4q25, and MCH3 to 10q25.
ISSN:0888-7543
1089-8646
DOI:10.1006/geno.1996.0476