New and old contrast agents: pharmacology, tissue opacification, and excretory urography

In equivalent doses for intravenous urograms conventional ionic contrast agents give iodine concentrations in the urine of approximately 30 mg iodine/ml, nonionic contrast media provide approximately 50 mg iodine/ml, and the ionic dimer Hexabrix approximately 70 mg iodine/mL. These new low osmolalit...

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Bibliographic Details
Published in:Urologic radiology 1988-01, Vol.10 (1), p.2-5
Main Author: SPATARO, R. F
Format: Article
Language:English
Subjects:
Biological and medical sciences
Contrast Media - pharmacology
Contrast media. Radiopharmaceuticals
Diatrizoate - pharmacology
Humans
Medical sciences
Osmolar Concentration
Pharmacology. Drug treatments
Radiographic Image Enhancement
Urography
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Summary:In equivalent doses for intravenous urograms conventional ionic contrast agents give iodine concentrations in the urine of approximately 30 mg iodine/ml, nonionic contrast media provide approximately 50 mg iodine/ml, and the ionic dimer Hexabrix approximately 70 mg iodine/mL. These new low osmolality, contrast media provide significantly higher urinary iodine concentrations than conventional ionic contrast media, provide better diagnostic quality excretory urograms, better patient tolerance, and fewer adverse side-effects and serious reactions. These new low osmolality, contrast media have significant advantages in intravenous urography in both safety and efficacy when compared to conventional higher osmolality contrast media.
ISSN:0171-1091
DOI:10.1007/BF02926526