Temporally changing patterns of hippocampal cerebral glucose utilization following sensorimotor cortical contusion in rats

Unilateral sensorimotor cortical contusion significantly decreased ipsilateral hippocampal cerebral metabolic rates of glucose utilization (CMRE glu) compared to sham controls at 2 and 16 days post injury. In contrast, hippocampal CMR glu was transiently increased at 6 days post injury. Both the inc...

Full description

Saved in:
Bibliographic Details
Published in:Brain research 1996-06, Vol.724 (2), p.246-250
Main Authors: Queen, Susan A., Feeney, Dennis M.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cerebral glucose metabolism
Contusions - metabolism
Cortical contusion
Densitometry
Glucose - metabolism
Hippocampal CA3 region
Hippocampus - metabolism
Injuries of the nervous system and the skull. Diseases due to physical agents
Kinetics
Male
Medical sciences
Motor Cortex - injuries
Rats
Rats, Sprague-Dawley
Somatosensory Cortex - injuries
Traumas. Diseases due to physical agents
Traumatic brain injury
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Unilateral sensorimotor cortical contusion significantly decreased ipsilateral hippocampal cerebral metabolic rates of glucose utilization (CMRE glu) compared to sham controls at 2 and 16 days post injury. In contrast, hippocampal CMR glu was transiently increased at 6 days post injury. Both the increased and decreased CMR glu were predominantly localized to the hippocampal CA3 subfield ipsilateral to injury and were significantly different from sham controls in the dorsal but not ventral hippocampal formation.
ISSN:0006-8993
1872-6240
DOI:10.1016/0006-8993(96)00308-3