RNA splicing: Unexpected spliceosome diversity

A novel form of spliceosome, containing the minor snRNPs U11 and U12, splices a class of pre-mRNA introns with non-consensus splice sites. This unexpected spliceosome diversity has interesting implications for the evolution and expression of eukaryotic genes.

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Bibliographic Details
Published in:Current biology 1996-07, Vol.6 (7), p.802-805
Main Authors: Kreivi, Jan-Peter, Lamond, Angus I
Format: Article
Language:English
Subjects:
Animals
Humans
Introns
Nuclear Proteins - genetics
Ribonucleoproteins, Small Nuclear - metabolism
RNA Precursors
RNA Splicing
Spliceosomes
tRNA Methyltransferases
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Description
Summary:A novel form of spliceosome, containing the minor snRNPs U11 and U12, splices a class of pre-mRNA introns with non-consensus splice sites. This unexpected spliceosome diversity has interesting implications for the evolution and expression of eukaryotic genes.
ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(02)00599-7